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Genetic Factors in Chronic Sinusitis

This study is currently recruiting participants.
Verified August 2016 by University of Chicago
Sponsor:
ClinicalTrials.gov Identifier:
NCT00880516
First Posted: April 13, 2009
Last Update Posted: August 26, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
University of Chicago
  Purpose
The purpose of this study is to learn more about the genetics of chronic sinusitis and identify genes involved in chronic sinusitis.

Condition
Chronic Sinusitis

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Genetic Factors in Chronic Sinusitis

Resource links provided by NLM:


Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Association of genetic variation with CRS disease status [ Time Frame: Adult age ]

Biospecimen Retention:   Samples With DNA
peripheral blood for DNA

Estimated Enrollment: 1200
Study Start Date: April 2009
Estimated Study Completion Date: March 2017
Estimated Primary Completion Date: March 2017 (Final data collection date for primary outcome measure)
Groups/Cohorts
control
Adults with normal sinuses
case
Adults with chronic sinusitis and positive findings on imaging.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Adults with and without chronic sinusitis
Criteria

Inclusion Criteria:

  • Age> 18 years
  • Diagnosis of chronic sinusitis or normal sinuses (with verification by imaging.) You must have a recent CT scan showing either normal sinuses or the presence of sinus disease.

Exclusion Criteria:

  • Genetic or acquired immunodeficiency
  • Ciliary dyskinesia
  • Cystic fibrosis
  • Autoimmune disease
  • Cancer of the sinuses
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00880516


Contacts
Contact: Marcy deTineo, BSN 773-702-5889 mdetineo@surgery.bsd.uchicago.edu

Locations
United States, Illinois
University of Chicago Recruiting
Chicago, Illinois, United States, 60637
Principal Investigator: Jayant Pinto, MD         
Sponsors and Collaborators
University of Chicago
Investigators
Principal Investigator: Jayant Pinto, MD University of Chicago
  More Information

Responsible Party: University of Chicago
ClinicalTrials.gov Identifier: NCT00880516     History of Changes
Other Study ID Numbers: 16749A
First Submitted: April 9, 2009
First Posted: April 13, 2009
Last Update Posted: August 26, 2016
Last Verified: August 2016

Additional relevant MeSH terms:
Sinusitis
Chronic Disease
Paranasal Sinus Diseases
Nose Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Otorhinolaryngologic Diseases
Disease Attributes
Pathologic Processes