Stellate Ganglion Nerve Block in Treating Women With Hot Flashes
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|ClinicalTrials.gov Identifier: NCT00879164|
Recruitment Status : Completed
First Posted : April 9, 2009
Last Update Posted : October 17, 2014
RATIONALE: A stellate ganglion nerve block may help relieve hot flashes in women.
PURPOSE: This clinical trial is studying how well a stellate ganglion nerve block works in treating women with hot flashes.
|Condition or disease||Intervention/treatment||Phase|
|Hot Flashes||Drug: bupivacaine hydrochloride Other: questionnaire administration||Early Phase 1|
- To evaluate the impact of stellate ganglion blockade on hot flash scores.
- To evaluate the toxicity of stellate ganglion blockade.
OUTLINE: Patients undergo fluoroscopic-guided stellate ganglion blockade using bupivacaine hydrochloride in week 1.
Patients complete a hot flash diary daily and a symptom experience diary weekly in weeks 1-7 and the Profile of Mood States questionnaire in weeks 1 and 7.
After completion of study treatment, patients are followed at 2 months and then monthly for 1 year.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||10 participants|
|Primary Purpose:||Supportive Care|
|Official Title:||Pilot Evaluation of a Stellate Ganglion Block for the Treatment of Hot Flashes|
|Study Start Date :||April 2009|
|Actual Primary Completion Date :||December 2010|
|Actual Study Completion Date :||December 2010|
- Difference in hot flash activity between baseline and week 7
- Difference in quality of life, toxicity, and self-assessment items between baseline and week 7
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00879164
|United States, Minnesota|
|Rochester, Minnesota, United States, 55905|
|Study Chair:||Charles L. Loprinzi, MD||Mayo Clinic|