Stellate Ganglion Nerve Block in Treating Women With Hot Flashes
|ClinicalTrials.gov Identifier: NCT00879164|
Recruitment Status : Completed
First Posted : April 9, 2009
Last Update Posted : October 17, 2014
RATIONALE: A stellate ganglion nerve block may help relieve hot flashes in women.
PURPOSE: This clinical trial is studying how well a stellate ganglion nerve block works in treating women with hot flashes.
|Condition or disease||Intervention/treatment||Phase|
|Hot Flashes||Drug: bupivacaine hydrochloride Other: questionnaire administration||Early Phase 1|
- To evaluate the impact of stellate ganglion blockade on hot flash scores.
- To evaluate the toxicity of stellate ganglion blockade.
OUTLINE: Patients undergo fluoroscopic-guided stellate ganglion blockade using bupivacaine hydrochloride in week 1.
Patients complete a hot flash diary daily and a symptom experience diary weekly in weeks 1-7 and the Profile of Mood States questionnaire in weeks 1 and 7.
After completion of study treatment, patients are followed at 2 months and then monthly for 1 year.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||10 participants|
|Primary Purpose:||Supportive Care|
|Official Title:||Pilot Evaluation of a Stellate Ganglion Block for the Treatment of Hot Flashes|
|Study Start Date :||April 2009|
|Primary Completion Date :||December 2010|
|Study Completion Date :||December 2010|
- Difference in hot flash activity between baseline and week 7
- Difference in quality of life, toxicity, and self-assessment items between baseline and week 7
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00879164
|United States, Minnesota|
|Rochester, Minnesota, United States, 55905|
|Study Chair:||Charles L. Loprinzi, MD||Mayo Clinic|