Stellate Ganglion Nerve Block in Treating Women With Hot Flashes
RATIONALE: A stellate ganglion nerve block may help relieve hot flashes in women.
PURPOSE: This clinical trial is studying how well a stellate ganglion nerve block works in treating women with hot flashes.
Drug: bupivacaine hydrochloride
Other: questionnaire administration
Early Phase 1
|Study Design:||Primary Purpose: Supportive Care|
|Official Title:||Pilot Evaluation of a Stellate Ganglion Block for the Treatment of Hot Flashes|
- Difference in hot flash activity between baseline and week 7
- Difference in quality of life, toxicity, and self-assessment items between baseline and week 7
|Study Start Date:||April 2009|
|Study Completion Date:||December 2010|
|Primary Completion Date:||December 2010 (Final data collection date for primary outcome measure)|
- To evaluate the impact of stellate ganglion blockade on hot flash scores.
- To evaluate the toxicity of stellate ganglion blockade.
OUTLINE: Patients undergo fluoroscopic-guided stellate ganglion blockade using bupivacaine hydrochloride in week 1.
Patients complete a hot flash diary daily and a symptom experience diary weekly in weeks 1-7 and the Profile of Mood States questionnaire in weeks 1 and 7.
After completion of study treatment, patients are followed at 2 months and then monthly for 1 year.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00879164
|United States, Minnesota|
|Rochester, Minnesota, United States, 55905|
|Study Chair:||Charles L. Loprinzi, MD||Mayo Clinic|