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Influence of Tonic and Burst Transcranial Magnetic Stimulation (TMS) Characteristics on Acute Inhibition of Subjective Tinnitus

This study has been completed.
Information provided by:
University Hospital, Antwerp Identifier:
First received: April 7, 2009
Last updated: April 8, 2009
Last verified: April 2009
Transcranial magnetic stimulation (TMS) is already broadly used in different areas of neuroscience research. Last year, special attention was drawn to TMS in tinnitus. The aim of the researchers' study is to investigate the stimulation characteristics of TMS in tinnitus patients, in particularly the effect of tonic and burst stimulation of the superior temporal lobe.

Condition Intervention
Procedure: TMS transcranial magnetic stimulation

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Influence of Tonic and Burst TMS Characteristics on Acute Inhibition of Subjective Tinnitus

Resource links provided by NLM:

Further study details as provided by University Hospital, Antwerp:

Primary Outcome Measures:
  • VAS visual analogue scale [ Time Frame: immediately before and immediately after single session TMS ]

Enrollment: 64
Study Start Date: January 2007
Study Completion Date: April 2008
Primary Completion Date: September 2007 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Tinnitus patients
Procedure: TMS transcranial magnetic stimulation

200 pulses of tonic TMS (see Graph 1) were administered with an intensity at 50% of the maximal TMS device output (50%DO).

The frequency of the tonic pulses was randomly chosen between 1Hz, 5Hz, 10Hz or 20Hz.

Burst stimulation was delivered at a burst frequency of 5, 10 or 20Hz. Each burst consisted of 3, 5 or 10 pulses. The individual pulse rate within a burst was 50 or 100Hz.


Ages Eligible for Study:   18 Years to 78 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients presented to our Multidisciplinary Tinnitus Clinic with tinnitus as a main complaint.

Inclusion Criteria:

  • Patients presented to our Multidisciplinary Tinnitus Clinic with tinnitus as a main complaint.

Exclusion Criteria:

  • Patients with known history of epilepsy, pacemakers, cochlear implants, neurostimulators or intracerebral pathology were excluded from the study.
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Please refer to this study by its identifier: NCT00878696

Antwerp University Hospital
Edegem, Antwerp, Belgium, 2650
Sponsors and Collaborators
University Hospital, Antwerp
  More Information

Responsible Party: Prof Van de Heyning, UZA Identifier: NCT00878696     History of Changes
Other Study ID Numbers: ITBTMS
Study First Received: April 7, 2009
Last Updated: April 8, 2009

Additional relevant MeSH terms:
Hearing Disorders
Ear Diseases
Otorhinolaryngologic Diseases
Sensation Disorders
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms processed this record on April 26, 2017