Histologic Evaluation of Bone Formation After Alveolar Augmentation by "Sandwich Osteotomy" Procedure for Dental Implants Insertion
Recruitment status was: Active, not recruiting
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||"Sandwich Osteotomy" Histologic Evaluation|
- Histologic slide evaluation of the bone on the dental implantation time [ Time Frame: implantation day (four months post bone augmentation) ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples Without DNA
|Study Start Date:||February 2009|
|Estimated Study Completion Date:||April 2011|
|Estimated Primary Completion Date:||April 2010 (Final data collection date for primary outcome measure)|
partially edentulous patients
Adult (post growth period) patients who are interested in fixed dental rehabilitation (non- removable denture) by dental implants.
Partially edentulous patients with insufficient bone height for dental implant insertion.
Dental implant use for partially edentolous jaw is a predictable procedure with high success rate. However, implantation procedure requires sufficient bone support both vertically and horizontally, and sometimes there is bone defect that requires bone augmentation prior to dental implant insertion.
There are some bone augmentation techniques known and used for this purposes, including: guided bone regeneration (GBR), distraction osteogenesis, split osteotomy, onlay bone graft, and interpositional bone graft.
One of the techniques is the interpositional bone graft using "sandwich osteotomy" technique, in which a cut is made in the bone (one horizontal and two vertical) separating a mobile bone portion which is fixed (using bone plate) in its new "ideal" position. The gap between the moved bone and the remaining bone is filled with xenograft ("bio-oss"). There is no documentation in the literature about histological evaluation of the bone after this well known clinical procedure. Four months after the bone augmentation procedure - the fixating plate is moved out and dental implants inserted. The first bur of the implantation (the smallest in the diameter) will be a trephine from which a histologic slide will be taken for check. The continuous dental implants insertion is the normal protocol for dental implantation (widening the recipient hole with bur, and insertion of the implant), followed by rehabilitation by prosthodontics.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00878332
|Hadassah Medical Organization|
|Principal Investigator:||Nardy Caspi, MD / DMD||Senior Lecturer oral and maxillofacial surgery|