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Copy Number Variations, Inflammatory Cytokines and the Risk of Dementia

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ClinicalTrials.gov Identifier: NCT00878280
Recruitment Status : Unknown
Verified April 2011 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
First Posted : April 8, 2009
Last Update Posted : April 22, 2011
Sponsor:
Information provided by:
National Taiwan University Hospital

Brief Summary:
Assess the association of copy number variation (CNV) and inflammatory cytokine with the risk of dementia.

Condition or disease
Dementia

Detailed Description:
This is a hospital-based case-control study. We plan to assess the association of CNV and inflammatory cytokine with the risk of dementia. Hopefully to find some genetic biomarkers to identify the risk of dementia at an early stage.

Study Type : Observational
Estimated Enrollment : 700 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Copy Number Variations, Expression of Inflammatory Cytokines and the Risk of Dementia - A Two-stage Genome-wide Association Study
Study Start Date : August 2008
Estimated Primary Completion Date : July 2011
Estimated Study Completion Date : July 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Dementia
U.S. FDA Resources

Group/Cohort
1
1:control(healthy subjects)
2
2:case(dementia patients)



Primary Outcome Measures :
  1. Dementia [ Time Frame: Aug 2008-July 2011 ]


Information from the National Library of Medicine

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Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
hospital recruited dementia patients and controls
Criteria

Inclusion Criteria:

  • hospital recruited dementia patients and controls

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00878280


Contacts
Contact: Yen-Ching Chen, ScD 886-2-33668019 chenkaren@yahoo.com

Locations
Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: yen-ching chen, ScD    3366-8019    chenkaren@yahoo.com   
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: yen-ching chen, ScD National Taiwan University Hospital

Responsible Party: Yen-Ching Chen, Institute of Preventive Medicine College of Public Health National Taiwan University
ClinicalTrials.gov Identifier: NCT00878280     History of Changes
Other Study ID Numbers: 200712102R-1
First Posted: April 8, 2009    Key Record Dates
Last Update Posted: April 22, 2011
Last Verified: April 2011

Additional relevant MeSH terms:
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders