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Copy Number Variations, Inflammatory Cytokines and the Risk of Dementia

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2011 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00878280
First Posted: April 8, 2009
Last Update Posted: April 22, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Taiwan University Hospital
  Purpose
Assess the association of copy number variation (CNV) and inflammatory cytokine with the risk of dementia.

Condition
Dementia

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Copy Number Variations, Expression of Inflammatory Cytokines and the Risk of Dementia - A Two-stage Genome-wide Association Study

Resource links provided by NLM:


Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • Dementia [ Time Frame: Aug 2008-July 2011 ]

Estimated Enrollment: 700
Study Start Date: August 2008
Estimated Study Completion Date: July 2011
Estimated Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
1:control(healthy subjects)
2
2:case(dementia patients)

Detailed Description:
This is a hospital-based case-control study. We plan to assess the association of CNV and inflammatory cytokine with the risk of dementia. Hopefully to find some genetic biomarkers to identify the risk of dementia at an early stage.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
hospital recruited dementia patients and controls
Criteria

Inclusion Criteria:

  • hospital recruited dementia patients and controls
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00878280


Contacts
Contact: Yen-Ching Chen, ScD 886-2-33668019 chenkaren@yahoo.com

Locations
Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: yen-ching chen, ScD    3366-8019    chenkaren@yahoo.com   
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: yen-ching chen, ScD National Taiwan University Hospital
  More Information

Responsible Party: Yen-Ching Chen, Institute of Preventive Medicine College of Public Health National Taiwan University
ClinicalTrials.gov Identifier: NCT00878280     History of Changes
Other Study ID Numbers: 200712102R-1
First Submitted: August 31, 2008
First Posted: April 8, 2009
Last Update Posted: April 22, 2011
Last Verified: April 2011

Additional relevant MeSH terms:
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders