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Copy Number Variations, Inflammatory Cytokines and the Risk of Dementia

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2011 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
Information provided by:
National Taiwan University Hospital Identifier:
First received: August 31, 2008
Last updated: April 21, 2011
Last verified: April 2011
Assess the association of copy number variation (CNV) and inflammatory cytokine with the risk of dementia.


Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Copy Number Variations, Expression of Inflammatory Cytokines and the Risk of Dementia - A Two-stage Genome-wide Association Study

Resource links provided by NLM:

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • Dementia [ Time Frame: Aug 2008-July 2011 ]

Estimated Enrollment: 700
Study Start Date: August 2008
Estimated Study Completion Date: July 2011
Estimated Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
1:control(healthy subjects)
2:case(dementia patients)

Detailed Description:
This is a hospital-based case-control study. We plan to assess the association of CNV and inflammatory cytokine with the risk of dementia. Hopefully to find some genetic biomarkers to identify the risk of dementia at an early stage.

Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
hospital recruited dementia patients and controls

Inclusion Criteria:

  • hospital recruited dementia patients and controls
  Contacts and Locations
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Please refer to this study by its identifier: NCT00878280

Contact: Yen-Ching Chen, ScD 886-2-33668019

National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: yen-ching chen, ScD    3366-8019   
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: yen-ching chen, ScD National Taiwan University Hospital
  More Information

Responsible Party: Yen-Ching Chen, Institute of Preventive Medicine College of Public Health National Taiwan University Identifier: NCT00878280     History of Changes
Other Study ID Numbers: 200712102R-1
Study First Received: August 31, 2008
Last Updated: April 21, 2011

Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders processed this record on May 25, 2017