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Effect of Combined Aerobic and Resisted Exercise in Breast Cancer Survivors

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ClinicalTrials.gov Identifier: NCT00877188
Recruitment Status : Completed
First Posted : April 7, 2009
Last Update Posted : December 21, 2012
Sponsor:
Information provided by (Responsible Party):
National Taiwan University Hospital

Brief Summary:
The purpose of this study is to evaluate the effects of a combined aerobic and resistance exercise program in breast cancer survivors.

Condition or disease Intervention/treatment Phase
Breast Cancer Exercise Physical Function Other: exercise Not Applicable

Detailed Description:
Cancer and cancer treatment side effects are associated with fatigue, pain, decreased cardiovascular fitness and muscle strength, and overall quality of life. Furthermore, cancer survivors are at increased risk for cancer recurrence and for secondary effect such as cardiovascular disease, diabetes, obesity, osteoporosis, and functional decline. Increase physical activity or exercise is proposed to overcome the negative psychological and physiological effects. Preliminary research evidence shows that exercise in cancer survivors improves quality of life, cardiorespiratory fitness, physical functioning, and decrease of fatigue. However, the best exercise mode and intensity has not been well established. Little is known regarding the long term effect. No study investigated impact of exercise for breast cancer survivors on upper extremity function, and correlation between fitness, upper extremity function and quality of life.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 34 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Effect of Combined Aerobic and Resisted Exercise in Breast Cancer Survivors: Upper Extremity Function, Quality of Life and Fitness Outcomes
Study Start Date : January 2009
Actual Primary Completion Date : October 2010
Actual Study Completion Date : December 2010

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: exercise
supervised combined aerobic and resistance training for 12 weeks
Other: exercise
supervised combined aerobic and progressive resistance training for 12 weeks

No Intervention: control
waist list control with usual care



Primary Outcome Measures :
  1. muscle fitness, quality of life, upper extremity function [ Time Frame: baseline, 12 weeks post exercise training and follow up 12 weeks ]


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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • stage 0 to II breast cancer diagnosed within 5 years
  • complete adjuvant therapy > 2 months, except hormone therapy
  • > 18 years

Exclusion Criteria:

  • disease in progress, recurrent, or metastasis
  • medical or musculoskeletal condition which resistance exercise is contraindicated
  • medication which may alter exercise response

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00877188


Locations
Taiwan
Graduate School of Physical Therapy, College of Medicine, NTU
Taipei, Taiwan
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Study Chair: Jau-Yih Tsauo, PHD Graduate School of Physical Therapy, College of Medicine, Nationall Taiwan University, Taipei, Taiwan

Responsible Party: National Taiwan University Hospital
ClinicalTrials.gov Identifier: NCT00877188     History of Changes
Other Study ID Numbers: 200808034R
NTUH98-M1178
First Posted: April 7, 2009    Key Record Dates
Last Update Posted: December 21, 2012
Last Verified: November 2012

Keywords provided by National Taiwan University Hospital:
breast cancer
exercise
upper extremity function
quality of life

Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Neoplasms
Breast Diseases
Skin Diseases