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Effect of Rosuvastatin Response in Healthy Subjects: Potential Mechanisms of Anti-inflammatory Effects

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2011 by University of Nebraska.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00874757
First Posted: April 2, 2009
Last Update Posted: October 12, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Nebraska
  Purpose
The purpose of this study is to see whether Statin drugs will act as anti-inflammatories. The investigators will study this potential anti-inflammatory activity in healthy subjects.

Condition
Healthy

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Effect of Rosuvastatin Response in Healthy Subjects: Potential Mechanisms of

Resource links provided by NLM:


Further study details as provided by University of Nebraska:

Estimated Enrollment: 20
Study Start Date: July 2009
Estimated Study Completion Date: December 2011
Estimated Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   19 Years to 39 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
20 healthy subjects
Criteria

Inclusion Criteria:

  • Healthy male non-asian subjects

Exclusion Criteria:

  • Patients with increased liver function tests, elevated serum creatinine, patients on anti-inflammatory or immunomodulating drugs
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00874757


Contacts
Contact: Timothy R McGuire, Pharm.D. 402-559-8224 trmcguir@unmc.edu
Contact: Paul Dobesh, Pharm.D. 402-559-1983 pdobesh@unmc.edu

Locations
United States, Nebraska
UNMC College of Pharmacy Recruiting
Omaha, Nebraska, United States, 68198-6045
Contact: Timothy R McGuire, Pharm.D.    402-559-8224    trmcguir@unmc.edu   
Contact: Paul Dobesh, Pharm.D.    402-559-1983    pdobesh@unmc.edu   
Sponsors and Collaborators
University of Nebraska
Investigators
Principal Investigator: Timothy R McGuire, PharmD University of Nebraska
  More Information

Responsible Party: Timothy R. McGuire, University of Nebraska College of Pharmacy
ClinicalTrials.gov Identifier: NCT00874757     History of Changes
Other Study ID Numbers: 088-09
First Submitted: April 1, 2009
First Posted: April 2, 2009
Last Update Posted: October 12, 2017
Last Verified: August 2011

Keywords provided by University of Nebraska:
Statins, anti-inflammatory
Healthy subjects study

Additional relevant MeSH terms:
Rosuvastatin Calcium
Anti-Inflammatory Agents
Anticholesteremic Agents
Hypolipidemic Agents
Antimetabolites
Molecular Mechanisms of Pharmacological Action
Lipid Regulating Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Enzyme Inhibitors