MRI in Assessing Tumor Size in Women With Ductal Carcinoma In Situ
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|ClinicalTrials.gov Identifier: NCT00874458|
Recruitment Status : Completed
First Posted : April 2, 2009
Last Update Posted : November 21, 2014
RATIONALE: Diagnostic procedures, such as MRI, may help find ductal carcinoma in situ and find out how far the disease has spread.
PURPOSE: This clinical trial is studying how well MRI works in assessing tumor size in women with ductal carcinoma in situ.
|Condition or disease||Intervention/treatment||Phase|
|Breast Cancer||Procedure: magnetic resonance imaging Procedure: radiomammography Procedure: ultrasound imaging||Not Applicable|
- Assess the contribution of MRI in accurately determining tumor size in women with ductal breast carcinoma in situ (DCIS).
- Evaluate the sensitivity of MRI in detecting DCIS.
- Evaluate the contribution of mammography in accurately determining tumor size.
- Compare the contribution of MRI vs mammography in assessing tumor extension.
- Compare the contribution of MRI vs mammography in assessing dense breasts.
- Evaluate the morphology of DCIS by MRI.
- Evaluate the curve of dynamic MRI in assessing DCIS.
- Evaluate the impact of nuclear grade of DCIS by MRI.
- Evaluate the rate of revision surgery.
OUTLINE: Patients undergo clinical examination, mammography, ultrasound imaging, unilateral breast MRI, and tissue sampling.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||40 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Ductal Carcinoma in Situ: Protocol Evaluating the Assessment of Extension of Disease by MRI|
|Study Start Date :||April 2007|
|Actual Primary Completion Date :||May 2011|
|Actual Study Completion Date :||December 2013|
|Experimental: MRI||Procedure: magnetic resonance imaging Procedure: radiomammography Procedure: ultrasound imaging|
- Correlation of tumor extension by MRI with surgical histology [ Time Frame: up to 1 year ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00874458
|Centre Antoine Lacassagne|
|Nice, France, 06189|
|Principal Investigator:||Claire Chapellier||Centre Antoine Lacassagne|