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Trial record 1 of 3 for:    "Wolff-Parkinson-White syndrome"
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Wolff-Parkinson-White Syndrome Anterograde Refractory Period of Accessory Duct (WPW)

This study has been terminated.
Information provided by (Responsible Party):
Nantes University Hospital Identifier:
First received: March 31, 2009
Last updated: February 7, 2013
Last verified: February 2013

The study consists of the realization of a new esophageal stimulation for patients already stimulated 10 years ago.

The investigators would like to make a long term evaluation of the evolution of anterograde effective refractory period of accessory duct in the WPW syndrome.

This study will be realized by esophageal stimulation.

Condition Intervention
Wolff-Parkinson-White Syndrome Procedure: esophagal stimulation

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Official Title: Long Term Evolution of the Anterograde Refractory Period of Accessory Duct in the Wolff-Parkinson-White Syndrome

Resource links provided by NLM:

Further study details as provided by Nantes University Hospital:

Primary Outcome Measures:
  • Measurement of effective anterograde refractory period of accessory duct and its evolution for a follow up superior to 10 years [ Time Frame: Day 0 ]

Secondary Outcome Measures:
  • Triggering a supra-ventricular tachycardia during the stimulation. [ Time Frame: Day 0 ]
  • Presence of symptoms linked to WPW syndrome during the interval separating the 2 esophageal stimulation. [ Time Frame: Day 0 ]

Enrollment: 13
Study Start Date: February 2009
Study Completion Date: December 2012
Primary Completion Date: December 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Stimulation
All patients included have the stimulation
Procedure: esophagal stimulation
ECG (rest) esophagal stimulation (rest and during effort)


Ages Eligible for Study:   21 Years to 64 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 21 < age < 64 years
  • First esophagal stimulation with evaluation of effective anterograde refractory period > 10 years
  • Informed consent signed
  • Diagnosis of Wolff-Parkinson-White syndrome
  • No procedure of ablation of accessory duct

Exclusion Criteria:

  • Ablation of accessory duct
  • Patient with contraindication to esophageal stimulation
  • Patient with contraindication to effort test
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Please refer to this study by its identifier: NCT00873470

Nantes UH
Nantes, France, 44093
Sponsors and Collaborators
Nantes University Hospital
  More Information

Responsible Party: Nantes University Hospital Identifier: NCT00873470     History of Changes
Other Study ID Numbers: BRD 08/9-I
Study First Received: March 31, 2009
Last Updated: February 7, 2013

Additional relevant MeSH terms:
Wolff-Parkinson-White Syndrome
Parkinson Disease
Pathologic Processes
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases
Pre-Excitation Syndromes
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Heart Defects, Congenital
Cardiovascular Abnormalities
Congenital Abnormalities processed this record on September 21, 2017