Wolff-Parkinson-White Syndrome Anterograde Refractory Period of Accessory Duct (WPW)

This study has been terminated.
Information provided by (Responsible Party):
Nantes University Hospital
ClinicalTrials.gov Identifier:
First received: March 31, 2009
Last updated: February 7, 2013
Last verified: February 2013

The study consists of the realization of a new esophageal stimulation for patients already stimulated 10 years ago.

The investigators would like to make a long term evaluation of the evolution of anterograde effective refractory period of accessory duct in the WPW syndrome.

This study will be realized by esophageal stimulation.

Condition Intervention
Wolff-Parkinson-White Syndrome
Procedure: esophagal stimulation

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Official Title: Long Term Evolution of the Anterograde Refractory Period of Accessory Duct in the Wolff-Parkinson-White Syndrome

Resource links provided by NLM:

Further study details as provided by Nantes University Hospital:

Primary Outcome Measures:
  • Measurement of effective anterograde refractory period of accessory duct and its evolution for a follow up superior to 10 years [ Time Frame: Day 0 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Triggering a supra-ventricular tachycardia during the stimulation. [ Time Frame: Day 0 ] [ Designated as safety issue: No ]
  • Presence of symptoms linked to WPW syndrome during the interval separating the 2 esophageal stimulation. [ Time Frame: Day 0 ] [ Designated as safety issue: No ]

Enrollment: 13
Study Start Date: February 2009
Study Completion Date: December 2012
Primary Completion Date: December 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Stimulation
All patients included have the stimulation
Procedure: esophagal stimulation
ECG (rest) esophagal stimulation (rest and during effort)


Ages Eligible for Study:   21 Years to 64 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 21 < age < 64 years
  • First esophagal stimulation with evaluation of effective anterograde refractory period > 10 years
  • Informed consent signed
  • Diagnosis of Wolff-Parkinson-White syndrome
  • No procedure of ablation of accessory duct

Exclusion Criteria:

  • Ablation of accessory duct
  • Patient with contraindication to esophageal stimulation
  • Patient with contraindication to effort test
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00873470

Nantes UH
Nantes, France, 44093
Sponsors and Collaborators
Nantes University Hospital
  More Information

Responsible Party: Nantes University Hospital
ClinicalTrials.gov Identifier: NCT00873470     History of Changes
Other Study ID Numbers: BRD 08/9-I 
Study First Received: March 31, 2009
Last Updated: February 7, 2013
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Additional relevant MeSH terms:
Parkinson Disease
Pre-Excitation Syndromes
Wolff-Parkinson-White Syndrome
Arrhythmias, Cardiac
Basal Ganglia Diseases
Brain Diseases
Cardiovascular Abnormalities
Cardiovascular Diseases
Central Nervous System Diseases
Congenital Abnormalities
Heart Defects, Congenital
Heart Diseases
Movement Disorders
Nervous System Diseases
Neurodegenerative Diseases
Parkinsonian Disorders
Pathologic Processes

ClinicalTrials.gov processed this record on May 26, 2016