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Risk Factors for Postpartum Psychosis (RIFPP)

This study has been completed.
Information provided by (Responsible Party):
Fu Zhou Wang, Nanjing Medical University Identifier:
First received: March 30, 2009
Last updated: January 11, 2014
Last verified: January 2014
A range of psychological disorders occur in women in the postpartum period. These include "the blues", which occurs in the first days after birth and which is very common and self-limiting; severe psychoses often associated with mania or bipolar illness, occurring in the first weeks after birth; and mild to moderate depression, occurring weeks to months after birth. Studies have been done focused on postpartum psychosis using a retrospective investigation, which gave only a limited material on the prevalence of psychological disorders in postpartum women. The investigators hypothesized that different pathways to psychosis function as the risk factors which may be overlapped, truly independent, mediating, or moderating, in new mothers who are at high risk and/or during the early period of delivery. In addition, the investigators purposed that the temporal sequence of biological, social and demographic variables are also the potential factors contributing to the development of postpartum psychosis.

Postpartum Period Psychosis

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Potential Risk Factors for Postpartum Psychosis

Resource links provided by NLM:

Further study details as provided by Fu Zhou Wang, Nanjing Medical University:

Primary Outcome Measures:
  • Incidence of psychoses [ Time Frame: 3 months and 6 months postpartum ]

Secondary Outcome Measures:
  • Antepartum economic level [ Time Frame: One year before labor and delivery (recorded by antepartum communication) ]
  • Antepartum social status [ Time Frame: One year before labor and delivery (recorded by antepartum communication) ]
  • Antepartum psychological level [ Time Frame: 1 day before birth ]
  • Intrapartum complications [ Time Frame: 1 day after birth ]
  • Baby characteristics [ Time Frame: One minute, 5min, 15min after baby was born ]
  • Maternal characteristics [ Time Frame: One day after birth ]
  • Medical caregiver characteristics [ Time Frame: One day before and after the labor completion ]
  • Parturient family characteristics [ Time Frame: One week before labor and delivery, recorded by investigators through patients' antepartum communication ]
  • Intrapartum medical procedures [ Time Frame: One day after birth ]

Enrollment: 4000
Study Start Date: February 2009
Study Completion Date: August 2012
Primary Completion Date: August 2012 (Final data collection date for primary outcome measure)
Psychoses within the first 3 months postpartum
Psychoses > 3 months to 6 months postpartum


Ages Eligible for Study:   18 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Parturients undergoing spontaneous or induced labor or cesarean delivery

Inclusion Criteria:

  • Pregnant women
  • Chinese

Exclusion Criteria:

  • Age < 18 years or > 50 years
  • Gestational age < 32 weeks
  Contacts and Locations
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Please refer to this study by its identifier: NCT00872313

China, Jiangsu
Nanjing Maternal and Child Health Care Hospital
Nanjing, Jiangsu, China, 210004
Sponsors and Collaborators
Nanjing Medical University
Study Director: XiaoFeng Shen, MD Nanjing Medical University
  More Information

Responsible Party: Fu Zhou Wang, Dr, Nanjing Medical University Identifier: NCT00872313     History of Changes
Other Study ID Numbers: NMU-200903-MZ003
Study First Received: March 30, 2009
Last Updated: January 11, 2014

Keywords provided by Fu Zhou Wang, Nanjing Medical University:
Postpartum Psychology

Additional relevant MeSH terms:
Psychotic Disorders
Mental Disorders
Schizophrenia Spectrum and Other Psychotic Disorders processed this record on September 20, 2017