Long-term Oxygen Treatment (LTOT) in Chronic Obstructive Pulmonary Disease: Factors Influencing Survival
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00871962|
Recruitment Status : Unknown
Verified June 2015 by Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche.
Recruitment status was: Active, not recruiting
First Posted : March 30, 2009
Last Update Posted : June 23, 2015
The purpose of this prospective cohort study is to determine factors involved in survival in new COPD patients treated by long-term oxygen therapy.
Background: long-term oxygen therapy is indicated in patients with severe COPD. No studies have been performed in the past 20-25 years to examine the results of early clinical trials. Further studies are necessary to understand the utility of oxygen therapy in severe COPD.
|Condition or disease||Intervention/treatment|
|Chronic Obstructive Pulmonary Disease||Other: OXYGEN SUPPLEMENTATION|
|Study Type :||Observational|
|Estimated Enrollment :||750 participants|
|Official Title:||Long-term Oxygen Treatment (LTOT) in Chronic Obstructive Pulmonary Disease: Factors Influencing Survival: Survival Factors in COPD Treated by Long-term Oxygen Therapy|
|Study Start Date :||June 2009|
|Estimated Primary Completion Date :||December 2015|
|Estimated Study Completion Date :||May 2016|
COPD patients on necessity of long-term oxygen therapy
Other: OXYGEN SUPPLEMENTATION
Patients treated by LTOT, with or without clinically fulfilled criteria for LTOT, with PaO2<55mmHg or less at rest or during sleeping or less during exercise, if supplemental oxygen is demonstrated to improve the exercise-associated hypoxia. Patients with PaO2 56-59mmHg if they also have dependent edema, pulmonary hypertension or hematocrit higher than 56%
Other Name: Patients with LTOT: survival
- Survival in function of initial hypoxemia, body mass index and cardiovascular events [ Time Frame: 3 years ]
- Long-term oxygen therapy observance and duration [ Time Frame: 3 years ]
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00871962
|Service de Pneumologie, Hôpital du Cluzeau|
|Limoges., France, 87042|
|Principal Investigator:||MELLONI Boris, Pr||Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche|