Point-of-Care Computed Tomography (CT) Chronic Rhinosinusitis Study
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|ClinicalTrials.gov Identifier: NCT00871286|
Recruitment Status : Completed
First Posted : March 30, 2009
Results First Posted : January 18, 2012
Last Update Posted : January 18, 2012
The purpose of this research study is to determine whether or not computed tomography (CT) scans performed on patients with symptoms of chronic rhinosinusitis (CRS) but without any physical signs of the disease will (1) prove to be less expensive in the treatment and evaluation as compared to current practices, (2) avoid the use of unnecessary antibiotic prescriptions, and (3) provide a more efficient way to diagnose conditions in patients who have had CRS ruled out as a cause.
The investigators hypothesize that current guidelines, when applied to subjects with symptoms of CRS in the absence of physical signs may be associated with (1) increased unnecessary prescription of antibiotics, (2) delay in further essential workup, and (3) increased overall health care costs.
|Condition or disease||Intervention/treatment||Phase|
|Chronic Rhinosinusitis||Procedure: Pre-treatment Sinus CT Scan Procedure: Post-treatment Sinus CT Scan||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||40 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Role of Point-of-Care CT Scanning in Patients Presenting With Symptoms of Chronic Rhinosinusitis|
|Study Start Date :||March 2009|
|Actual Primary Completion Date :||August 2010|
|Actual Study Completion Date :||August 2010|
Experimental: CT scan (sinus) pre-tx
Sinus CT scan performed at initial otolaryngology (ear, nose, and throat)visit
Procedure: Pre-treatment Sinus CT Scan
Pre-treatment Sinus CT Scan
CT scan (sinus) post-tx
Sinus CT scan performed after 3-4 weeks of antibiotic treatment and any other indicated medical treatment(s), per insurance company guidelines
Procedure: Post-treatment Sinus CT Scan
Post-treatment Sinus CT Scan
- Number of Participants in Compliance With Medical Recommendations [ Time Frame: 8 weeks ]Number of participants in each group who complied with medical advice given at the initial appointment.
- Number of Participants Having a CT Done [ Time Frame: 8 weeks ]Total number of participants having a CT scan (sinus) done in each of the two groups over the study interval.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00871286
|United States, Illinois|
|Northwestern University/Northwestern Medical Faculty Foundation|
|Chicago, Illinois, United States, 60611|
|Principal Investigator:||Rakesh K Chandra, MD||Northwestern University, Northwestern Medical Faculty Foundation, Northwestern Memorial Hospital|