Point-of-Care Computed Tomography (CT) Chronic Rhinosinusitis Study
The purpose of this research study is to determine whether or not computed tomography (CT) scans performed on patients with symptoms of chronic rhinosinusitis (CRS) but without any physical signs of the disease will (1) prove to be less expensive in the treatment and evaluation as compared to current practices, (2) avoid the use of unnecessary antibiotic prescriptions, and (3) provide a more efficient way to diagnose conditions in patients who have had CRS ruled out as a cause.
The investigators hypothesize that current guidelines, when applied to subjects with symptoms of CRS in the absence of physical signs may be associated with (1) increased unnecessary prescription of antibiotics, (2) delay in further essential workup, and (3) increased overall health care costs.
|Chronic Rhinosinusitis||Procedure: Pre-treatment Sinus CT Scan Procedure: Post-treatment Sinus CT Scan|
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
|Official Title:||Role of Point-of-Care CT Scanning in Patients Presenting With Symptoms of Chronic Rhinosinusitis|
- Number of Participants in Compliance With Medical Recommendations [ Time Frame: 8 weeks ]Number of participants in each group who complied with medical advice given at the initial appointment.
- Number of Participants Having a CT Done [ Time Frame: 8 weeks ]Total number of participants having a CT scan (sinus) done in each of the two groups over the study interval.
|Study Start Date:||March 2009|
|Study Completion Date:||August 2010|
|Primary Completion Date:||August 2010 (Final data collection date for primary outcome measure)|
Experimental: CT scan (sinus) pre-tx
Sinus CT scan performed at initial otolaryngology (ear, nose, and throat)visit
Procedure: Pre-treatment Sinus CT Scan
Pre-treatment Sinus CT Scan
CT scan (sinus) post-tx
Sinus CT scan performed after 3-4 weeks of antibiotic treatment and any other indicated medical treatment(s), per insurance company guidelines
Procedure: Post-treatment Sinus CT Scan
Post-treatment Sinus CT Scan
Please refer to this study by its ClinicalTrials.gov identifier: NCT00871286
|United States, Illinois|
|Northwestern University/Northwestern Medical Faculty Foundation|
|Chicago, Illinois, United States, 60611|
|Principal Investigator:||Rakesh K Chandra, MD||Northwestern University, Northwestern Medical Faculty Foundation, Northwestern Memorial Hospital|