A to Z Study Follow-up: Collection of DNA Data From Buccal Swabs
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00866151 |
Recruitment Status : Unknown
Verified March 2009 by Interleukin Genetics, Inc..
Recruitment status was: Enrolling by invitation
First Posted : March 20, 2009
Last Update Posted : March 20, 2009
|
- Study Details
- Tabular View
- Results Submitted
- Disclaimer
- How to Read a Study Record
Condition or disease |
---|
Weight Management Diet Conditions Dietary Recommendations Overweight Management Obesity |
Study Type : | Observational |
Estimated Enrollment : | 150 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Official Title: | A to Z Study Follow-up: Collection of DNA Data From Buccal Swabs |
Study Start Date : | August 2008 |
Estimated Primary Completion Date : | June 2009 |
Estimated Study Completion Date : | September 2009 |
Group/Cohort |
---|
1
Previously enrolled subjects in the "Benefits and Risks of Alternative Weight Loss Strategies - a Clinical Trial", which was run at Stanford 2003-2005. (A to Z Study)
|
- The PRIMARY objective of this study is to identify genotype-diet interaction on weight, body fat, and BMI. [ Time Frame: 1 year ]
- The SECONDARY objective is to explore the association of single nucleotide polymorphisms (SNPs) with other metabolic parameters, such as blood lipid profile, insulin level, and other cardiovascular risk factors. [ Time Frame: 1 year ]
Biospecimen Retention: Samples With DNA

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 25 Years to 50 Years (Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- BMI (body mass index): 27-40 kg/m2
- Gender: Women only
- Age: 25-50
- Menopausal status: pre-menopausal
- Weight stable for last 2-months
- Not on a weight loss plan
- No ethnic restrictions
- No plans to move from the area over the next 6-months
- Willing to accept random assignment
- Possess English speaking and reading skills to understand and complete forms such as informed consent and study evaluation
Exclusion Criteria:
- Hypertension
- Diabetes (type 1 or 2) or history of gestational diabetes
- Heart disease diagnosis
- Renal or lever disease
- Active neoplasms
- Pregnant, lactating, within 6-months of birth, or planning to become pregnant in the next 6-months
- Hyperthyroidism, unless treated and under control
- Medications known to affect weight / energy expenditure
- Excessive alcohol intake (self-reported, > 3 drinks/day)
- Postmenopausal, including surgical menopause
- Currently under psychiatric care, or severely clinically depressed (>17 on Beck Inventory)

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00866151
United States, California | |
Stanford University | |
Stanford, California, United States, 94305-5401 |
Principal Investigator: | Christopher Gardner, PhD | Stanford University |
Responsible Party: | Karen Shaver / Director of Clinical Operations, Interleukin Genetics Inc., |
ClinicalTrials.gov Identifier: | NCT00866151 |
Other Study ID Numbers: |
ILI-08-108WMGTP 14895 |
First Posted: | March 20, 2009 Key Record Dates |
Last Update Posted: | March 20, 2009 |
Last Verified: | March 2009 |
genetic biomarker biomarker molecular diagnostics genes genetics |
overweight management weight management weight reduction SNPs single nucleotide polymorphisms |
Overweight Body Weight |