Eyelid Position Interdependence in Involutional Ptosis Patients Submitted to 10% Phenylephrine
The primary aim of this study is to quantify eyelid position changes in tested and opposite eyes in ptosis patients submitted to 1, 2 or 4 drops of 10% phenylephrine in one eye. The secondary objective is to correlate the eye dominance, severity and laterality of ptosis with eyelid position changes in these 3 groups.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Comparative Study of Eyelid Position Interdependence in Involutional Ptosis Patients Submitted to 1, 2 or 4 Drops of 10% Phenylephrine|
- Upper lid height before and after phenylephrine test lower lid height before and after phenylephrine test [ Time Frame: 3, 10, 15 and 30 minutes ] [ Designated as safety issue: Yes ]
- Scobee test to detect eye dominance [ Time Frame: 15 minutes before 10% phenylephrine instillation ] [ Designated as safety issue: Yes ]
|Study Start Date:||September 2006|
|Study Completion Date:||March 2009|
|Primary Completion Date:||March 2009 (Final data collection date for primary outcome measure)|
Patients submitted to application of 1 drop of 10% phenylephrine
Patients submitted to application of 2 drops of 10% phenylephrine
Patients submitted to application of 4 drops of 10% phenylephrine
This is a prospective observational study conducted in involutional ptosis patients, which will be submitted to instillation of a single drop of 10% phenylephrine in one eye(Group 1), 2 drops (G2) or 4 drops ( G3).
Video camera will record the images of both eyes before and after drug application at 3, 10, 15 and 30 minutes. The images will be edited to analyze upper and lower lid height.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00864656
|Ophthalmology Dept. University of Sao Paulo General Hospital|
|Sao Paulo, Brazil, 05403010|
|Principal Investigator:||Suzana Matayoshi, MD||Opthalmology Dept.Sao Paulo University General Hospital|