Corneal Endothelium After Glaucoma Surgery
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ClinicalTrials.gov Identifier: NCT00863018 |
Recruitment Status
:
Completed
First Posted
: March 17, 2009
Last Update Posted
: July 29, 2015
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Condition or disease |
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Glaucoma Corneal Damage Intraocular Pressure |
Study Type : | Observational |
Actual Enrollment : | 61 participants |
Observational Model: | Case Control |
Time Perspective: | Prospective |
Official Title: | Change in Corneal Endothelium After Glaucoma Surgery; Trabeculectomy and Glaucoma Implant Surgery |
Study Start Date : | August 2003 |
Actual Primary Completion Date : | August 2008 |
Actual Study Completion Date : | January 2009 |

Group/Cohort |
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Control
Eyes with glaucoma and on anti-glaucoma medication but without glaucoma surgery
|
Implant surgery
Eyes underwent Ahmed glaucoma valve implantation
|
Trabeculectomy
Eyes underwent conventional trabeculectomy with mitomycin-C
|
- Change in corneal endothelial cell density, hexagonality, and coefficient of variation of cell area [ Time Frame: 1 and 2 years longitudinal follow up ]
- Clinical factors associated with the damage of corneal endothelium after glaucoma surgery [ Time Frame: 1 and 2 years longitudinal follow up ]

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Ages Eligible for Study: | 20 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- Patients who need glaucoma surgery for intraocular pressure control
Exclusion Criteria:
- congenital glaucoma
- Pre-existing corneal abnormality
- lost from follow up without any ocular problem within 6 months from surgery

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00863018
Korea, Republic of | |
Chungnam National University Hospital | |
Daejeon, Korea, Republic of, 301-721 |
Study Director: | Young-ha Lee, MD, PhD | Research Institute for Medical Science, Chungnam National University | |
Principal Investigator: | Chang-sik Kim, MD, PhD | Ophthalmology, College of Medicine, Chungnam National University |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Chang-sik Kim, professor, Chungnam National University |
ClinicalTrials.gov Identifier: | NCT00863018 History of Changes |
Other Study ID Numbers: |
CNUMC-09-04 |
First Posted: | March 17, 2009 Key Record Dates |
Last Update Posted: | July 29, 2015 |
Last Verified: | July 2015 |
Keywords provided by Chang-sik Kim, Chungnam National University:
Corneal endothelial cell Specular microscopy Glaucoma implant surgery Ahmed glaucoma valve Trabeculectomy |
Additional relevant MeSH terms:
Glaucoma Corneal Injuries Ocular Hypertension Eye Diseases Eye Injuries Facial Injuries |
Craniocerebral Trauma Trauma, Nervous System Nervous System Diseases Corneal Diseases Wounds and Injuries |