Parkinson's Disease Genetics Database
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|ClinicalTrials.gov Identifier: NCT00855556|
Recruitment Status : Terminated (Enrollment into this registry was not as robust as investigator envisioned. Thus, the registry was closed.)
First Posted : March 4, 2009
Last Update Posted : September 16, 2015
The goal of the study is to develop and organize an effort to identify genes that determine an individual's risk for developing Parkinson's disease (PD).
- To ascertain, study and establish a repository of DNA samples that will allow for the identification of known and yet-to-be-identified genetic markers associated with the development of PD.
- To create a database with clinical, genetic (HLA, genome screen) and medical history information that will facilitate the search for PD susceptibility genes.
- To provide a centralized DNA repository to allow for targeted studies of genetic factors contributing to the onset, heterogeneity and progression of PD.
- To evaluate opportunities to extend the results of research to develop methods of risk prediction, prevention and therapy for PD.
|Condition or disease||Intervention/treatment|
|Parkinson's Disease||Genetic: blood draw|
|Study Type :||Observational|
|Actual Enrollment :||16 participants|
|Official Title:||Parkinson's Disease Genetics Database|
|Study Start Date :||February 2008|
|Actual Primary Completion Date :||February 2013|
|Actual Study Completion Date :||February 2013|
- Genetic: blood draw
The blood collection is designed to obtain blood samples as a source of DNA for genotyping and to establish a plasma and serum storage repository for future assays. GCRC nurses will perform all blood draws associated with this study. The following procedures are designed to standardize sample collection:
- Blood will be collected with the participant in the seated position with the reclining position reserved for those with a history of fainting during blood collection.
- Participants will be instructed to drink plenty of water (e.g., at least 8 large glasses of water) prior to the clinic visit as this facilitates easier collection.
- No fasting, activity or medication restrictions are required prior to or following blood collection.
- Blood collection will follow completion of the questionnaires. They will be performed by a nurse or technician with documented class time and experience in phlebotomy. Technician certification will occur prior to blood collection.
- the current protocol is for establishment of the registry only and not for particular analyses of its contents [ Time Frame: 5 years ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00855556
|United States, New York|
|The Feinstein Institute for Medical Research|
|Manhasset, New York, United States, 11030|
|Principal Investigator:||Michael Pourfar, MD||Northwell Health|