Parkinson's Disease Genetics Database
|ClinicalTrials.gov Identifier: NCT00855556|
Recruitment Status : Terminated (Enrollment into this registry was not as robust as investigator envisioned. Thus, the registry was closed.)
First Posted : March 4, 2009
Last Update Posted : September 16, 2015
The goal of the study is to develop and organize an effort to identify genes that determine an individual's risk for developing Parkinson's disease (PD).
- To ascertain, study and establish a repository of DNA samples that will allow for the identification of known and yet-to-be-identified genetic markers associated with the development of PD.
- To create a database with clinical, genetic (HLA, genome screen) and medical history information that will facilitate the search for PD susceptibility genes.
- To provide a centralized DNA repository to allow for targeted studies of genetic factors contributing to the onset, heterogeneity and progression of PD.
- To evaluate opportunities to extend the results of research to develop methods of risk prediction, prevention and therapy for PD.
|Condition or disease||Intervention/treatment|
|Parkinson's Disease||Genetic: blood draw|
|Study Type :||Observational|
|Actual Enrollment :||16 participants|
|Official Title:||Parkinson's Disease Genetics Database|
|Study Start Date :||February 2008|
|Primary Completion Date :||February 2013|
|Study Completion Date :||February 2013|
Genetic: blood draw
- Blood will be collected with the participant in the seated position with the reclining position reserved for those with a history of fainting during blood collection.
- Participants will be instructed to drink plenty of water (e.g., at least 8 large glasses of water) prior to the clinic visit as this facilitates easier collection.
- No fasting, activity or medication restrictions are required prior to or following blood collection.
- Blood collection will follow completion of the questionnaires. They will be performed by a nurse or technician with documented class time and experience in phlebotomy. Technician certification will occur prior to blood collection.
The blood collection is designed to obtain blood samples as a source of DNA for genotyping and to establish a plasma and serum storage repository for future assays. GCRC nurses will perform all blood draws associated with this study. The following procedures are designed to standardize sample collection:
- the current protocol is for establishment of the registry only and not for particular analyses of its contents [ Time Frame: 5 years ]
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00855556
|United States, New York|
|The Feinstein Institute for Medical Research|
|Manhasset, New York, United States, 11030|
|Principal Investigator:||Michael Pourfar, MD||Northwell Health|