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Lung Transplantation in Respiratory Failure Patients

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ClinicalTrials.gov Identifier: NCT00854165
Recruitment Status : Unknown
Verified March 2009 by National Taiwan University Hospital.
Recruitment status was:  Active, not recruiting
First Posted : March 3, 2009
Last Update Posted : March 3, 2009
Sponsor:
Information provided by:
National Taiwan University Hospital

Brief Summary:
Survival after cadaveric lung transplantation in recipients depended on ventilation support prior to transplantation has been reported to have relative high surgical mortality and morbidity rate. The objectives of this study were to describe the short-term outcomes of bilateral sequential lung transplantation under extracorporeal membrane oxygenation (ECMO) support in a consecutive series of patients who depended on noninvasive and invasive ventilation support preoperatively .

Condition or disease
Respiratory Failure

Detailed Description:
The one-year survival rate and postoperative pulmonary functional results will be reported in this study.

Study Type : Observational
Actual Enrollment : 10 participants
Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Extracorporeal Membrane Oxygenation Support for Bilateral Sequential Lung Transplantation in Respiratory Failure Patients.
Study Start Date : February 2009
Estimated Primary Completion Date : April 2009
Estimated Study Completion Date : June 2009

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. 6 months and one year survival after lung transplatn. [ Time Frame: 6 months and one year posttransplant ]

Secondary Outcome Measures :
  1. Pulmonary function results, at baseline and posttransplant 1, 3, and 6 months. [ Time Frame: baseline, post-op 1,3, and 6 months ]


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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Between July 2006 and July 2008, we performed bilateral sequential lung transplantation under venoarterious ECMO support in 10 respiratory failure patients with various lung diseases. This study wanted to report the preoperative condition, postoperative complications, and short-term outcome after lung transplantation.
Criteria

Inclusion Criteria:

  • respiratory patients depended on ventilator supports prior to lung transplant

Exclusion Criteria:

  • non-cardaveric lung transplant

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00854165


Locations
Taiwan
Department of Surgery, National Taiwan University Hospital
Taipei, Taiwan, 100
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Study Director: Yung-Chie Lee, MD, PhD Department of Surgery, National Taiwan University Hospital
Principal Investigator: Hsao-Hsun Hsu, MD Department of Surgery, National Taiwan University Hospital

Responsible Party: Yung-Chie Lee, Department of Surgery
ClinicalTrials.gov Identifier: NCT00854165     History of Changes
Other Study ID Numbers: 200901015R
First Posted: March 3, 2009    Key Record Dates
Last Update Posted: March 3, 2009
Last Verified: March 2009

Keywords provided by National Taiwan University Hospital:
lung transplantation
respiratory failure
ECMO
Lung transplants in respiratory failure patients

Additional relevant MeSH terms:
Respiratory Insufficiency
Respiration Disorders
Respiratory Tract Diseases