Cardiorespiratory Changes in Patients Being Weaned Off Mechanical Ventilation
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|ClinicalTrials.gov Identifier: NCT00852891|
Recruitment Status : Completed
First Posted : February 27, 2009
Last Update Posted : February 27, 2009
|Condition or disease|
|Critical Care Weaning|
Weaning from mechanical ventilation (MV) involves physiological changes that can overload the cardiorespiratory system due to changes in the interaction between patient and ventilator.
This was a randomized crossover clinical trial that included patients in an intensive care unit (ICU) who had been on MV for more than 48 hours and who were considered ready for weaning. Cardiorespiratory variables, oxygenation, electrocardiogram (ECG) and Doppler echocardiogram findings were analyzed at baseline and after 30 minutes in each trial weaning method (PSV and T-tube). Comparisons were made between PSV and T-tube, weaning success and failure and patients with and without heart disease, using ANOVA and Student's t test. The level of significance was set at p < 0.05.
|Study Type :||Observational|
|Actual Enrollment :||24 participants|
|Official Title:||Cardiorespiratory Changes in Patients Being Weaned Off Mechanical Ventilation: a Randomized Crossover Clinical Trial|
|Study Start Date :||December 2005|
|Actual Study Completion Date :||August 2007|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00852891
|Federal University of Rio Grande do Sul|
|Porto Alegre, RS, Brazil|
|Principal Investigator:||Silvia RR Vieira, PhD||Hospital de Clínicas de Porto Alegre|