Coronary Bifurcation Stenting (COBIS) Registry in South Korea

This study has been completed.
Information provided by (Responsible Party):
Hyeon-Cheol Gwon, Samsung Medical Center Identifier:
First received: February 25, 2009
Last updated: July 15, 2012
Last verified: July 2012

The COBIS registry is multi-center, real-world registry of drug-eluting stenting in coronary bifurcation lesions in South Korea.

The aim of the study was to find out the current status of bifurcation drug-eluting stenting and determine the prognostic factors for long-term outcome in South Korea.

Coronary Bifurcation Lesion

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Coronary Bifurcation Stenting (COBIS) Registry in South Korea

Further study details as provided by Samsung Medical Center:

Primary Outcome Measures:
  • Incidence of the composite outcome of all-cause death, MI, or any PCI/CABG [ Time Frame: 3 years ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • Incidence of stent thrombosis, and periprocedural MI [ Time Frame: 3 years ] [ Designated as safety issue: Yes ]

Enrollment: 1919
Study Start Date: January 2004
Study Completion Date: December 2008
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Coronary bifurcation lesion


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients with coronary bifurcation lesion treated with drug-eluting stents

Inclusion Criteria:

  • Age >= 18 years
  • Any type of de novo bifurcation lesion with a parent vessel >= 2.5 mm and side branch>= 2.0 mm by visual estimation
  • Treated with drug-eluting stent

Exclusion Criteria:

  • Cardiogenic Shock
  • ST elevation MI within 48hours
  • Expected survival less than 1 year
  • Left main bifurcation
  • Allergy to the antiplatelets
  Contacts and Locations
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Please refer to this study by its identifier: NCT00851526

Korea, Republic of
Samsung Medical Center
Seoul, Korea, Republic of, 135-710
Sponsors and Collaborators
Samsung Medical Center
  More Information

No publications provided by Samsung Medical Center

Additional publications automatically indexed to this study by Identifier (NCT Number):

Responsible Party: Hyeon-Cheol Gwon, Professor, Samsung Medical Center Identifier: NCT00851526     History of Changes
Other Study ID Numbers: 2007-04-042
Study First Received: February 25, 2009
Last Updated: July 15, 2012
Health Authority: Korea: Food and Drug Administration

Keywords provided by Samsung Medical Center:
Coronary bifurcation lesion
Drug-eluting stent processed this record on November 27, 2015