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Microarray Analysis of Sinus Samples From Patients With and Without Chronic Rhinosinusitis.

This study has been completed.
Information provided by:
University of California, San Francisco Identifier:
First received: February 18, 2009
Last updated: NA
Last verified: February 2009
History: No changes posted
The purpose of this study is to compare the bacteria, fungi, and viruses that are present in the sinuses of patients with chronic rhinosinusitis to patients without sinus disease using a new technology, called a microarray, that will allow more accurate identification of microorganisms than current laboratory methods.

Chronic Rhinosinusitis

Study Type: Observational
Official Title: Microarray Analysis of Sinus Samples From Patients With and Without Chronic Rhinosinusitis.

Further study details as provided by University of California, San Francisco:


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Twenty total patients are being recruited: ten adult patients who meet the clinical criteria for chronic rhinosinusitis requiring surgical therapy and ten adult patients undergoing either orbital decompression for Graves' orbitopathy or maxillomandibular advancement for obstructive sleep apnea, with no history of sinus disease.

Inclusion Criteria:

  • Age 18 years or older
  • History of chronic rhinosinusitis (CRS)
  • Impaired CRS-specific quality of life
  • Evidence of sinus disease on a CT scan

Exclusion Criteria:

  • Control patients with any evidence of CRS by history, survey, or imaging criteria
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

Responsible Party: Department of Otolaryngology - Head and Neck Surgery, University of California, San Francisco Identifier: NCT00847041     History of Changes
Other Study ID Numbers: A109753
Study First Received: February 18, 2009
Last Updated: February 18, 2009

Additional relevant MeSH terms:
Paranasal Sinus Diseases
Nose Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Otorhinolaryngologic Diseases processed this record on April 28, 2017