Neuronal Processing of Diacritics: An fMRI Study

This study has been completed.

Sponsor:

Information provided by (Responsible Party):

Mitchell Albert, University of Massachusetts, Worcester

ClinicalTrials.gov Identifier:

NCT00845806

First received: February 16, 2009

Last updated: November 3, 2011

Last verified: November 2011

History of Changes

Purpose

The purpose of this study is to determine brain function in reading arabic diacritics.

Condition	Intervention
Neuronal Processing of Diacritics	Other: MRI


Study Type:	Observational
Study Design:	Observational Model: Case-Only
Official Title:	Neuronal Processing of Diacritics: An fMRI Study

Further study details as provided by University of Massachusetts, Worcester:

Primary Outcome Measures:

Observe regional brain function from reading Arabic diacritics [ Time Frame: 1 hour ] [ Designated as safety issue: No ]


Enrollment:	12
Study Start Date:	February 2009
Study Completion Date:	February 2011
Primary Completion Date:	February 2011 (Final data collection date for primary outcome measure)

Groups/Cohorts	Assigned Interventions
Arabic Speakers All subjects must be male native arabic speakers who can read and speak english.	Other: MRI All subjects will be asked to lay in an MRI for about an hour while reading Arabic diacritic characters Other Names: Arabic Diacritic fMRI

Detailed Description:

fMRI is a well established imaging technique that allows investigators to see regional brain function based off of actions like reading, speaking, playing music, etc. Even the type of language and format of that language can change the area of the brain that is active while performing that action. This study is meant to see the areas of the brain that become active both prior to and during the process of reading diacritic markings in arabic.

Eligibility


Ages Eligible for Study:	18 Years and older (Adult, Senior)
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

All subjects will be male native arabic speakers that can read and write english. All will be healthy with no history of neurological or psychiatric disorders.

Criteria

Inclusion Criteria

Adult patients may be enrolled in this study if they meet the following inclusion criteria:

Are male and are 18 years or older, inclusive;
Consent from the patient
First language is Arabic
Must be able to speak and read English
Right handed
The subject must pass a dyslexia screen test (Attached to consent form).

Exclusion Criteria

Adult patients will be excluded from this study if they do not fulfill the inclusion criteria, or if any of the following conditions have been met:

Have any contraindications to an MR exam such as a pace-maker, metallic cardiac valves, magnetic material (i.e., surgical clips) implanted electronic infusion pumps or any other conditions that would preclude proximity to a strong magnetic field;
Are undergoing the MR exam in an emergency situation
People with psychiatric disorders will be excluded from the study.
Are claustrophobic and can not tolerate the imaging.
People with neurological diseases
Are on any medications for psychiatric, neurological, or chronic pain problems.

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00845806

Locations


United States, Massachusetts
UMASS Medical School Advanced MRI Center
Worcester, Massachusetts, United States, 01655

Sponsors and Collaborators

University of Massachusetts, Worcester

Investigators


Principal Investigator:	Mitchell S Albert, Ph.D.	UMASS Medical School

More Information


Responsible Party:	Mitchell Albert, Director of Advanced MRI Center, UMASS Medical Sch, University of Massachusetts, Worcester
ClinicalTrials.gov Identifier:	NCT00845806 History of Changes
Other Study ID Numbers:	Docket # 13127
Study First Received:	February 16, 2009
Last Updated:	November 3, 2011
Health Authority:	United States: Institutional Review Board

Keywords provided by University of Massachusetts, Worcester:


Diacritics Neuronal Processing fMRI Arabic

ClinicalTrials.gov processed this record on September 23, 2016

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