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Racial Differences in Orthostatic Tolerance

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00844181
First Posted: February 16, 2009
Last Update Posted: February 16, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Yale University
  Purpose
Our central hypothesis is that baroreflex sensitivity is attenuated in black women compared to white women, and that this dysregulation will be apparent during orthostatic challenges. We expect that the cumulative stress index (CSI), a measure of maximal orthostatic tolerance, is higher in Black women (BW) compared to White women (WW).

Condition
Orthostatic Tolerance

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Racial Differences in Orthostatic Tolerance

Further study details as provided by Yale University:

Primary Outcome Measures:
  • orthostatic tolerance [ Time Frame: 1 ]

Biospecimen Retention:   Samples With DNA
whole blood

Enrollment: 18
Study Start Date: October 2007
Study Completion Date: January 2009
Primary Completion Date: January 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
0
white women
1
Black women

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 25 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Community sample of women of reproductive age
Criteria

Inclusion Criteria:

  • women between 18-25 yrs of age

Exclusion Criteria:

  • history of high blood pressure, uterine fibroids, diabetes, epilepsy
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00844181


Locations
United States, Connecticut
John B. Pierce Laboratory
New Haven, Connecticut, United States, 06519
Sponsors and Collaborators
Yale University
Investigators
Principal Investigator: Nina Stachenfeld, PhD Yale University
  More Information

Responsible Party: Nina Stachenfeld, PhD, John B. Pierce Laboratory
ClinicalTrials.gov Identifier: NCT00844181     History of Changes
Other Study ID Numbers: 0512000875
3R01HL071159-04A1S1 ( U.S. NIH Grant/Contract )
First Submitted: February 13, 2009
First Posted: February 16, 2009
Last Update Posted: February 16, 2009
Last Verified: February 2009