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Racial Differences in Orthostatic Tolerance

This study has been completed.
Information provided by:
Yale University Identifier:
First received: February 13, 2009
Last updated: NA
Last verified: February 2009
History: No changes posted
Our central hypothesis is that baroreflex sensitivity is attenuated in black women compared to white women, and that this dysregulation will be apparent during orthostatic challenges. We expect that the cumulative stress index (CSI), a measure of maximal orthostatic tolerance, is higher in Black women (BW) compared to White women (WW).

Orthostatic Tolerance

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Racial Differences in Orthostatic Tolerance

Further study details as provided by Yale University:

Primary Outcome Measures:
  • orthostatic tolerance [ Time Frame: 1 ]

Biospecimen Retention:   Samples With DNA
whole blood

Enrollment: 18
Study Start Date: October 2007
Study Completion Date: January 2009
Primary Completion Date: January 2009 (Final data collection date for primary outcome measure)
white women
Black women


Ages Eligible for Study:   18 Years to 25 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Community sample of women of reproductive age

Inclusion Criteria:

  • women between 18-25 yrs of age

Exclusion Criteria:

  • history of high blood pressure, uterine fibroids, diabetes, epilepsy
  Contacts and Locations
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Please refer to this study by its identifier: NCT00844181

United States, Connecticut
John B. Pierce Laboratory
New Haven, Connecticut, United States, 06519
Sponsors and Collaborators
Yale University
Principal Investigator: Nina Stachenfeld, PhD Yale University
  More Information

Responsible Party: Nina Stachenfeld, PhD, John B. Pierce Laboratory Identifier: NCT00844181     History of Changes
Other Study ID Numbers: 0512000875
3R01HL071159-04A1S1 ( U.S. NIH Grant/Contract )
Study First Received: February 13, 2009
Last Updated: February 13, 2009 processed this record on August 18, 2017