Osteogenic Cell Viability in Bone Graft
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ClinicalTrials.gov Identifier: NCT00843973 |
Recruitment Status
:
Completed
First Posted
: February 13, 2009
Last Update Posted
: June 21, 2017
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Condition or disease | Intervention/treatment |
---|---|
Fractures, Closed | Procedure: iliac crest bone graft Procedure: Reamer Irrigator Aspirator |
Study Type : | Observational |
Actual Enrollment : | 83 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Official Title: | Osteogenic Cell Viability in Bone Graft Obtained Using the Reamer Irrigator Aspirator (RIA) System Versus Iliac Crest Bone Graft |
Study Start Date : | June 2008 |
Actual Primary Completion Date : | October 2011 |
Actual Study Completion Date : | December 2013 |

Group/Cohort | Intervention/treatment |
---|---|
iliac crest bone graft
Bone graft harvested via iliac crest bone graft procedure
|
Procedure: iliac crest bone graft
iliac crest bone graft procedure
Other Name: ICBG
|
Reamer Irrigator Aspirator
Bone graft harvested via the Reamer Irrigator Aspirator (RIA) Procedure
|
Procedure: Reamer Irrigator Aspirator
Reamer Irrigator Aspirator (RIA) Procedure
Other Name: RIA
|
- Cell viability [ Time Frame: 1 hour post-collection ]
- Osteogenic potential [ Time Frame: 1 hour post-collection ]

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Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- Subjects age 18 years or older
- Subjects undergoing a bone grafting procedure, either using an iliac crest or RIA system harvesting technique, or
- Subjects undergoing reamed femoral intramedullary nailing using the RIA reaming technique
Exclusion Criteria:
- Subjects under age 18
- Subjects with a history of: leukemia; cancer with bone metastases; renal failure, receiving dialysis; or on immunosuppressive medications

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00843973
United States, Missouri | |
University of Missouri | |
Columbia, Missouri, United States, 65212 |
Principal Investigator: | Brett D Crist, MD | University of Missouri-Columbia |
Responsible Party: | Brett Crist, Assistant Professor, Co-Director of Trauma Services, Co-Director Orthopaedic Trauma Fellowship, Department of Orthopaedic Surgery, University of Missouri-Columbia |
ClinicalTrials.gov Identifier: | NCT00843973 History of Changes |
Other Study ID Numbers: |
IRB 1095798 |
First Posted: | February 13, 2009 Key Record Dates |
Last Update Posted: | June 21, 2017 |
Last Verified: | June 2017 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Keywords provided by Brett Crist, University of Missouri-Columbia:
Iliac Crest Bone Graft Reamer Irrigator Aspirator |
Additional relevant MeSH terms:
Fractures, Closed Fractures, Bone Wounds and Injuries |