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Trefoil Peptides in Lung Diseases

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified February 2009 by Bispebjerg Hospital.
Recruitment status was:  Recruiting
Information provided by:
Bispebjerg Hospital Identifier:
First received: February 6, 2009
Last updated: NA
Last verified: February 2009
History: No changes posted
The study focuses on trefoil family factor (TFF) peptides in sputum in lung diseases. The investigators hypothesize that TFF peptides are upregulated in lung diseases characterized by mucus hypersecretion.

Chronic Obstructive Pulmonary Disease Asthma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Trefoil Peptides in Lung Diseases

Resource links provided by NLM:

Further study details as provided by Bispebjerg Hospital:

Primary Outcome Measures:
  • TFF in sputum [ Time Frame: Monthly ]

Estimated Enrollment: 60
Study Start Date: February 2009
Estimated Study Completion Date: May 2010
Estimated Primary Completion Date: May 2010 (Final data collection date for primary outcome measure)
Chronic obstructive pulmonary disease
Healthy controls


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Subjects with chronic obstruction pulmonary disease (COPD) Subjects with asthma Healthy volunteers

Inclusion Criteria:

  • Age 18 years or older
  • Informed consent

Exclusion Criteria:

  • Upper and lower airway infection 2 weeks prior to visit 1
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00839735

Contact: Thomas K Lund, MD PhD (+45) 35 31 30 69
Contact: Lars Pedersen, MD PhD (+45) 35 31 30 69

Respiratory and Allergy Research Unit, Department of Respiratory Medicine L, Bispebjerg Hospital Recruiting
Copenhagen, Denmark, 2400
Contact: Thomas K Lund, MD PhD    (+45) 35 31 30 69   
Sponsors and Collaborators
Bispebjerg Hospital
Principal Investigator: Thomas K Lund, MD PhD Respiratory and Allergy Research Unit
  More Information

Responsible Party: Thomas K. Lund (MD PhD) & Lars Pedersen (MD PhD), Respiratory and Allergy Research Unit, Department of Respiratory Medicine, Bispebjerg Hospital, Copenhagen, Denmark Identifier: NCT00839735     History of Changes
Other Study ID Numbers: H-B-2008-120
Study First Received: February 6, 2009
Last Updated: February 6, 2009

Keywords provided by Bispebjerg Hospital:

Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases processed this record on August 16, 2017