Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury
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|ClinicalTrials.gov Identifier: NCT00837057|
Recruitment Status : Unknown
Verified January 2009 by Asan Medical Center.
Recruitment status was: Not yet recruiting
First Posted : February 5, 2009
Last Update Posted : February 5, 2009
Severe sepsis or septic shock with acute kidney injury shows high mortality in intensive care unit. A few studies have shown CRRT relating the clinical improvement seems to be related to the early initiation of therapy. But there is no consensus for proper time of CRRT may improve the prognosis.
The study is a prospective randomized one center trial comparing two treatments in patients suffering from septic shock complicated with acute renal failure admitted to ICU, treated either early by CRRT (35 ml/kg/h) or by conventional RRT.
|Condition or disease||Intervention/treatment||Phase|
|Severe Sepsis Septic Shock Acute Kidney Injury||Procedure: crrt||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||60 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||A Randomized Controlled Multi-Center Trial of the Early Application of CRRT in Patients With Severe Sepsis or Septic Shock|
|Study Start Date :||February 2009|
|Estimated Primary Completion Date :||January 2011|
|early crrt, late crrt||
early CRRT (35 ml/kg/h)& acute kidney injury or failure or nearly anuria more than 2hr or late conventional dialysis indication
Other Name: renal replacement therapy, timing
- Death from all causes at 28 days after randomisation [ Time Frame: 28 day ]
- Death within the in the intensive care unit. Death within 90 days of randomisation. Death prior to hospital discharge. Length of ICU stay. The need for and duration of other organ support [ Time Frame: 90 day ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00837057
|Contact: sangbum hong, firstname.lastname@example.org|
|Korea, Republic of|
|Asan Medical Center||Not yet recruiting|
|Seoul, Korea, Republic of|
|Contact: sangbum hong, md 82-2-3010-3893 email@example.com|
|Principal Investigator: sangbum hong, md|