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Mesenchymal Stem Cells: Alterations in Genome (MESSAGE)

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ClinicalTrials.gov Identifier: NCT00836732
Recruitment Status : Completed
First Posted : February 4, 2009
Last Update Posted : September 30, 2013
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The aim is to study small genetic alterations induced by cell culture in human mesenchymal stem cells in GMP condition.

Condition or disease Intervention/treatment
Pened Chest Surgery for Programmes Coronary Bypass Procedure: harvest of a small bone marrow sample

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 35 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Official Title: MESenchymal Stem Cells: Alterations in GEnome
Study Start Date : November 2008
Primary Completion Date : March 2012
Study Completion Date : March 2012
Arms and Interventions

Intervention Details:
    Procedure: harvest of a small bone marrow sample
    harvest of a small bone marrow sample during open chest surgery

Outcome Measures

Primary Outcome Measures :
  1. Presence of small genetic alteration in mesenchymal stem cells [ Time Frame: one month ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • age > 18 old
  • age < 75 old
  • opened chest surgery for programmed coronary bypass
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00836732


Locations
France
nantes University Hospital
Nantes, France, 44340
Sponsors and Collaborators
Nantes University Hospital
Investigators
Principal Investigator: Patricia Lemarchand, MD Nantes UH - institut du thorax
More Information

Responsible Party: Nantes University Hospital
ClinicalTrials.gov Identifier: NCT00836732     History of Changes
Other Study ID Numbers: BRD 08/9-S
First Posted: February 4, 2009    Key Record Dates
Last Update Posted: September 30, 2013
Last Verified: September 2013

Keywords provided by Nantes University Hospital:
celle therapy
cell culture
mesenchymal stem cells