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Mesenchymal Stem Cells: Alterations in Genome (MESSAGE)

This study has been completed.
Information provided by (Responsible Party):
Nantes University Hospital Identifier:
First received: February 3, 2009
Last updated: September 27, 2013
Last verified: September 2013
The aim is to study small genetic alterations induced by cell culture in human mesenchymal stem cells in GMP condition.

Condition Intervention
Pened Chest Surgery for Programmes Coronary Bypass
Procedure: harvest of a small bone marrow sample

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Official Title: MESenchymal Stem Cells: Alterations in GEnome

Further study details as provided by Nantes University Hospital:

Primary Outcome Measures:
  • Presence of small genetic alteration in mesenchymal stem cells [ Time Frame: one month ]

Enrollment: 35
Study Start Date: November 2008
Study Completion Date: March 2012
Primary Completion Date: March 2012 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: harvest of a small bone marrow sample
    harvest of a small bone marrow sample during open chest surgery

Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • age > 18 old
  • age < 75 old
  • opened chest surgery for programmed coronary bypass
  Contacts and Locations
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Please refer to this study by its identifier: NCT00836732

nantes University Hospital
Nantes, France, 44340
Sponsors and Collaborators
Nantes University Hospital
Principal Investigator: Patricia Lemarchand, MD Nantes UH - institut du thorax
  More Information

Responsible Party: Nantes University Hospital Identifier: NCT00836732     History of Changes
Other Study ID Numbers: BRD 08/9-S
Study First Received: February 3, 2009
Last Updated: September 27, 2013

Keywords provided by Nantes University Hospital:
celle therapy
cell culture
mesenchymal stem cells processed this record on May 22, 2017