Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis Impact (SNA&Sepsis)
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|ClinicalTrials.gov Identifier: NCT00835913|
Recruitment Status : Completed
First Posted : February 4, 2009
Last Update Posted : January 19, 2015
|Condition or disease||Phase|
|Septic Shock Severe Sepsis||Phase 4|
Our principal aim is to characterize modulation of cardiac sympathic nervous system in sepsis through the study of sinusal change and myocardiac fixing of MIBG.
The second aim is 1)to assess links between alteration of cardiac sympathic nervous system and NT-PRoBNP variations in sepsis and 2)To know prognostic impact in sympathic nervous system compare to NTproBNP.
|Study Type :||Observational|
|Actual Enrollment :||13 participants|
|Official Title:||Autonomic Nervous System Alteration Induce by Sepsis:Assessment and Prognosis Impact|
|Study Start Date :||October 2008|
|Primary Completion Date :||September 2011|
|Study Completion Date :||September 2011|
- Sinusal variability analysis and myocardic fixation of MIBG performed in 48 hours post admission [ Time Frame: 48 hours post admission ]
- plasmatic measure of NT-ProBNP and catecholamine at admission, day 2 and last day of hospitalisation [ Time Frame: 30 days ]
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00835913
|University Hospital Grenoble|
|Grenoble, France, 38000|
|Principal Investigator:||SCHWEBEL Carole, PH||Unit intensive care|