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Multi Marker Approach Interest in Emergency in Acute Respiratory Insufficiency Diagnostic (BIO-IRA)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00835809
First Posted: February 4, 2009
Last Update Posted: September 8, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Regional Clinical Research
Information provided by:
University Hospital, Grenoble
  Purpose

Biomarkers have an interest in clinic diagnostic ,therapeutic and prognosis in pathophysiologic situation including cardiovascular.But interest of biomarkers in diagnostic care of severe acute respiratory insufficiency remains to clear.

We propose to determine the more relevant marker combination in this case.


Condition
Acute Respiratory Insufficiency

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Multi Marker Approach Interest in Emergency in Acute Respiratory Insufficiency Diagnostic

Resource links provided by NLM:


Further study details as provided by University Hospital, Grenoble:

Biospecimen Retention:   Samples With DNA
Protein sample

Enrollment: 400
Study Start Date: October 2008
Study Completion Date: October 2009
Primary Completion Date: October 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
Acute respiratory diseases.
Patient admit in emergency or intensive care unite with acute respiratory insufficiency.

Detailed Description:

In urgence of a severe acute respiratory insufficiency,for thanks to an approach diagnostic, therapeutic and prognostic we propose to determine the more relevant biomarker combination.

An expert committee will compare the biomarker diagnostic and prognostic relevance thanks to all elements clinico-biological and patient monitoring.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Emergency and unit intensive care patient.
Criteria

Inclusion Criteria:

  • Oxygen saturation below or equal to 92% in ambient air.
  • Respiratory frequence above 25 cycle per minute

Exclusion Criteria:

  • Minors
  • Pregnant or lactating women
  • Patient without social security
  • Patient hospitalize without consent
  • Chest pain with acute coronary electro-cardiographic change leading immediate achievement of a diagnostic coronary angiography and/or therapeutic
  • Pneumothorax
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00835809


Locations
France
University Hospital Grenoble
Grenoble, France, 38000
Sponsors and Collaborators
University Hospital, Grenoble
Regional Clinical Research
Investigators
Principal Investigator: ARA SOMOHANO Claire, PH Emergency NGO Onlus
  More Information

Responsible Party: Ms Claire ARA SOMOHANO, Service de réanimation médicale
ClinicalTrials.gov Identifier: NCT00835809     History of Changes
Other Study ID Numbers: 0811
2008-A00703-52 ( Registry Identifier: ID RCB )
First Submitted: February 3, 2009
First Posted: February 4, 2009
Last Update Posted: September 8, 2010
Last Verified: September 2010

Keywords provided by University Hospital, Grenoble:
Acute respiratory insufficiency respiratory
Biomarkers
Emergency
Intensive care unit
Prospective
Patient hospitalize in emergency or in intensive care unit
for acute respiratory insufficiency

Additional relevant MeSH terms:
Emergencies
Respiratory Insufficiency
Pulmonary Valve Insufficiency
Disease Attributes
Pathologic Processes
Respiration Disorders
Respiratory Tract Diseases
Heart Valve Diseases
Heart Diseases
Cardiovascular Diseases