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Multi Marker Approach Interest in Emergency in Acute Respiratory Insufficiency Diagnostic (BIO-IRA)

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ClinicalTrials.gov Identifier: NCT00835809
Recruitment Status : Completed
First Posted : February 4, 2009
Last Update Posted : September 8, 2010
Sponsor:
Collaborator:
Regional Clinical Research
Information provided by:
University Hospital, Grenoble

Brief Summary:

Biomarkers have an interest in clinic diagnostic ,therapeutic and prognosis in pathophysiologic situation including cardiovascular.But interest of biomarkers in diagnostic care of severe acute respiratory insufficiency remains to clear.

We propose to determine the more relevant marker combination in this case.


Condition or disease
Acute Respiratory Insufficiency

Detailed Description:

In urgence of a severe acute respiratory insufficiency,for thanks to an approach diagnostic, therapeutic and prognostic we propose to determine the more relevant biomarker combination.

An expert committee will compare the biomarker diagnostic and prognostic relevance thanks to all elements clinico-biological and patient monitoring.


Study Type : Observational
Actual Enrollment : 400 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Multi Marker Approach Interest in Emergency in Acute Respiratory Insufficiency Diagnostic
Study Start Date : October 2008
Actual Primary Completion Date : October 2009
Actual Study Completion Date : October 2009

Resource links provided by the National Library of Medicine


Group/Cohort
Acute respiratory diseases.
Patient admit in emergency or intensive care unite with acute respiratory insufficiency.



Biospecimen Retention:   Samples With DNA
Protein sample


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Emergency and unit intensive care patient.
Criteria

Inclusion Criteria:

  • Oxygen saturation below or equal to 92% in ambient air.
  • Respiratory frequence above 25 cycle per minute

Exclusion Criteria:

  • Minors
  • Pregnant or lactating women
  • Patient without social security
  • Patient hospitalize without consent
  • Chest pain with acute coronary electro-cardiographic change leading immediate achievement of a diagnostic coronary angiography and/or therapeutic
  • Pneumothorax

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00835809


Locations
France
University Hospital Grenoble
Grenoble, France, 38000
Sponsors and Collaborators
University Hospital, Grenoble
Regional Clinical Research
Investigators
Principal Investigator: ARA SOMOHANO Claire, PH Emergency NGO Onlus

Responsible Party: Ms Claire ARA SOMOHANO, Service de réanimation médicale
ClinicalTrials.gov Identifier: NCT00835809     History of Changes
Other Study ID Numbers: 0811
2008-A00703-52 ( Registry Identifier: ID RCB )
First Posted: February 4, 2009    Key Record Dates
Last Update Posted: September 8, 2010
Last Verified: September 2010

Keywords provided by University Hospital, Grenoble:
Acute respiratory insufficiency respiratory
Biomarkers
Emergency
Intensive care unit
Prospective
Patient hospitalize in emergency or in intensive care unit
for acute respiratory insufficiency

Additional relevant MeSH terms:
Emergencies
Respiratory Insufficiency
Pulmonary Valve Insufficiency
Disease Attributes
Pathologic Processes
Respiration Disorders
Respiratory Tract Diseases
Heart Valve Diseases
Heart Diseases
Cardiovascular Diseases