Biomarkers for Obstructive Sleep Apnea (BOSA)
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|ClinicalTrials.gov Identifier: NCT00834509|
Recruitment Status : Completed
First Posted : February 3, 2009
Last Update Posted : April 18, 2017
The purpose of the study is to:
- recruit subjects with untreated sleep apnea; assess overnight changes in their blood and urine chemicals
- review the overnight changes in blood and urine chemicals after they have been treated for sleep apnea
- assess the overnight changes in blood and urine chemicals in healthy individuals with no sleep problems
- compare the amount of fat in the belly using a Magnetic Resonance Imaging (MRI) scanner on all subjects
|Condition or disease||Intervention/treatment|
|Obstructive Sleep Apnea (OSA)||Device: CPAP|
|Study Type :||Observational|
|Actual Enrollment :||181 participants|
|Official Title:||Towards a Blood Test for Diagnosis of Obstructive Sleep Apnea|
|Study Start Date :||April 2008|
|Actual Primary Completion Date :||February 1, 2015|
|Actual Study Completion Date :||February 1, 2015|
Obstructive Sleep Apnea (OSA)
OSA participants will be treated with a CPAP/APAP treatment, per standard clinical care.
Use CPAP for 4-6 weeks as clinically prescribed.
Control participants will not receive APAP/CPAP treatment, if not diagnosed with OSA.
- Magnitude of change in biomarkers during sleep in persons with OSA before & after successful treatment with CPAP, & differences in magnitude of change in persons with different degrees of visceral adiposity, & in those w/ & w/o specific comorbidities. [ Time Frame: End of study ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00834509
|United States, Pennsylvania|
|University of Pennsylvania|
|Philadelphia, Pennsylvania, United States, 19104|
|Principal Investigator:||Allan I Pack, MD||University of Pennsylvania|