Influence of Non-steroidal Anti-inflammatory Drugs (NSAID) on Muscle Regeneration
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ClinicalTrials.gov Identifier: NCT00832663 |
Recruitment Status
:
Completed
First Posted
: January 30, 2009
Last Update Posted
: March 16, 2010
|
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The purpose of this study is to determine the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on muscle regeneration.
The investigators' hypothesis is that ingestion of NSAID will delay or impair muscle regeneration.
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Muscle Damage | Drug: NSAID Drug: placebo | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 32 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Triple (Participant, Investigator, Outcomes Assessor) |
Primary Purpose: | Basic Science |
Official Title: | The Influence of Blocking Inflammatory Activity in Vivo on Skeletal Muscle Regeneration in Humans |
Study Start Date : | April 2009 |
Actual Primary Completion Date : | December 2009 |
Actual Study Completion Date : | December 2009 |
Arm | Intervention/treatment |
---|---|
Experimental: NSAID
receive NSAID
|
Drug: NSAID
Effect of NSAID ingestion on muscle regeneration
|
Placebo Comparator: Placebo
receive placebo
|
Drug: placebo
receive placebo
|
- Muscle regeneration [ Time Frame: 1 month ]
- Muscle strength [ Time Frame: 1 month ]

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Ages Eligible for Study: | 18 Years to 35 Years (Adult) |
Sexes Eligible for Study: | Male |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- male
- healthy
- does not exercise regularly
Exclusion Criteria:
- displays contraindications for taking NSAID
- well-trained

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00832663
Denmark | |
Bispebjerg Hospital | |
Copenhagen, NV, Denmark, 2400 |
Principal Investigator: | Abigail L Mackey, PhD | Institute of Sports Medicine Copenhagen, Bispebjerg Hospital |
Responsible Party: | Abigail Mackey, Institute of Sports Medicine Copenhagen |
ClinicalTrials.gov Identifier: | NCT00832663 History of Changes |
Other Study ID Numbers: |
AM_P64_BBH H-D-2008-074 |
First Posted: | January 30, 2009 Key Record Dates |
Last Update Posted: | March 16, 2010 |
Last Verified: | March 2010 |
Keywords provided by Bispebjerg Hospital:
Muscle regeneration Satellite cells electrical stimulation eccentric contractions myogenic precursor cells |
Additional relevant MeSH terms:
Anti-Inflammatory Agents, Non-Steroidal Analgesics, Non-Narcotic Analgesics Sensory System Agents |
Peripheral Nervous System Agents Physiological Effects of Drugs Anti-Inflammatory Agents Antirheumatic Agents |