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Screening Scottish Swimmers for Asthma and Rhinitis (CLE004)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00831428
First Posted: January 29, 2009
Last Update Posted: September 23, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Dundee
  Purpose
The Scottish National and District swimming teams will be screened for asthma and rhinitis using both mannitol challenge and sport-based exercise challenge.

Condition Intervention
Asthma Rhinitis Other: no intervention

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: A Pilot Study to Identify the Prevalence of Exercise- Induced Asthma and Rhinitis in Scottish Swimmers, Using Mannitol Challenge as a Screening Tool.

Resource links provided by NLM:


Further study details as provided by University of Dundee:

Primary Outcome Measures:
  • Tidal Nitric Oxide [ Time Frame: This test will be performed prior to entering the pool, and on exiting the pool ]

Secondary Outcome Measures:
  • Mannitol Challenge [ Time Frame: This test will be performed once on a district and once on a national squad training day ]
  • Sport-based Challenge [ Time Frame: This test will be performed once on a district and once on a national squad training day ]
  • Nasal Nitric Oxide [ Time Frame: This test will be performed prior to entering the pool, and on exiting the pool ]
  • Skin Prick Test [ Time Frame: This test will be performed once on a district and once on a national squad training day ]
  • Mini Nasal Lavage [ Time Frame: This test will be performed prior to entering the pool, and on exiting the pool ]

Enrollment: 97
Study Start Date: February 2009
Study Completion Date: June 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Scottish swimming team Other: no intervention
this is a screening study, not an interventional study

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   11 Years to 23 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
The Scottish national and district swimming teams
Criteria

Inclusion Criteria:

  • member of the Scottish national and district swimming team
  • informed consent obtained

Exclusion Criteria:

  • pregnant, lactating or planning to become pregnant
  • concomitant use of medicines (prescribed, over-the-counter or herbal) that may interfere with the trial.
  • any clinically significant medical condition, as deemed by the clinical investigators, which may endanger the health of the participant or jeopardise the protocol.
  • inability to comply with the protocol.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00831428


Locations
United Kingdom
The national swimming academy in Stirling
Stirling, Stirlingshire, United Kingdom, FK9 4LA
Sponsors and Collaborators
University of Dundee
Investigators
Principal Investigator: Karine L Clearie, MBBS, MRCP Asthma and Allergy Research Group
Study Director: Brian J Lipworth, MBchB Asthma and Allergy Research Group
  More Information

Responsible Party: Dr Karine Clearie, Asthma and Allergy Research Group
ClinicalTrials.gov Identifier: NCT00831428     History of Changes
Other Study ID Numbers: CLE004
First Submitted: January 28, 2009
First Posted: January 29, 2009
Results First Submitted: August 11, 2011
Results First Posted: September 23, 2011
Last Update Posted: September 23, 2011
Last Verified: May 2009

Keywords provided by University of Dundee:
asthma
rhinitis
swimmers
mannitol

Additional relevant MeSH terms:
Asthma
Rhinitis
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases
Nose Diseases
Respiratory Tract Infections
Otorhinolaryngologic Diseases
Mannitol
Diuretics, Osmotic
Diuretics
Natriuretic Agents
Physiological Effects of Drugs