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Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic Disorders

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details. Identifier: NCT00830557
Recruitment Status : Recruiting
First Posted : January 28, 2009
Last Update Posted : October 18, 2018
National Cancer Institute (NCI)
Information provided by (Responsible Party):
Gloria M. Petersen, Mayo Clinic

Brief Summary:

RATIONALE: Gathering medical information and collecting and storing samples of blood and tissue to test in the laboratory may help doctors develop better ways to screen people at risk for pancreatic cancer or other pancreatic disorders in the future.

PURPOSE: This clinical trial is collecting medical information and tissue samples from patients with pancreatic cancer or other pancreatic disorders.

Condition or disease Intervention/treatment
Islet Cell Tumor Pancreatic Cancer Pancreatic Disease Other: medical chart review Other: survey administration Other: biospecimen collection

Detailed Description:



  • To collect clinical data and family histories and blood and/or tissue samples from patients diagnosed with pancreatic diseases, including pancreatic cancer, for use in future studies.
  • To collect information regarding food preparation and intake in these patients.


  • To make available to researchers medical data and biospecimens to enable them to develop better ways to screen people at risk for pancreatic conditions, including pancreatic cancer.
  • To investigate genes or substances that increase susceptibility of developing pancreatic conditions.
  • To find agents that may help prevent, treat, or cure these conditions.
  • To learn whether inherited factors increase the risk of pancreatic diseases, pancreatic cancer, or other cancers.

OUTLINE: This is a multicenter study.

Patients complete two 1-hour surveys assessing health, clinical and family history of pancreatic conditions including cancer, and food preparation and intake. Patients also complete a 15- to 30-minute follow up survey at 6 months and 1 year to assess health, health practices, and family history. A review of the patient's medical information is obtained from the medical record.

Blood samples are collected for future research studies. Oral cells and stool samples may also be collected for future studies.

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Study Type : Observational
Estimated Enrollment : 7500 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Biospecimen Resource for Pancreas Research, a Data & Tissue Bank (Also Known as a Bio-repository, Bio-bank, Data & Tissue Database, Data & Tissue Registry, Etc.) to Help Advance Research in Pancreas Disease
Study Start Date : October 2000
Estimated Primary Completion Date : September 2022
Estimated Study Completion Date : September 2022

Intervention Details:
  • Other: medical chart review
    baseline, 12 month and 36 months
  • Other: survey administration
    baseline, 6 month, 12 month
  • Other: biospecimen collection

Primary Outcome Measures :
  1. Collection of clinical data, health and family histories by survey [ Time Frame: baseline enrollment, 6 months, 12 months ]
  2. Collection of blood and/or tissue, fecal and oral specimens [ Time Frame: baseline ]
  3. Collection of information regarding food preparation and intake by survey [ Time Frame: baseline ]

Biospecimen Retention:   Samples With DNA
Two 10mL plasma tubes, two 10mL serum tubes and one 10mL heparin tube collected. DNA extracted from lymphocytes. Possible saliva collection for DNA extraction. Waste tissue from prior surgery may be collected. Stool samples may be collected.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 120 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Pancreas disease patients


  • Diagnosis or suspicion of at least one of the following:

    • Pancreatic cancer
    • Pancreatic mass
    • Islet cell tumor
    • Intraductal papillary mucinous neoplasms (IPMN)
    • Hereditary pancreatitis


  • Able to understand and read English
  • Mentally competent and able to provide informed consent
  • Has not donated blood within the past 8 weeks


  • At least 7 days since prior blood transfusion
  • At least 7 days since prior surgery

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00830557

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Contact: Cindy Beinhorn 1-800-914-7962
Contact: Bridget Rathbun 1-800-914-7962

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United States, Minnesota
Mayo Clinic Cancer Center Recruiting
Rochester, Minnesota, United States, 55905
Contact: Clinical Trials Office - All Mayo Clinic Locations    507-538-7623      
Sponsors and Collaborators
Mayo Clinic
National Cancer Institute (NCI)
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Principal Investigator: Gloria M. Petersen, PhD, FACMG Mayo Clinic

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Responsible Party: Gloria M. Petersen, PhD, Mayo Clinic Identifier: NCT00830557     History of Changes
Other Study ID Numbers: 354-06
P50CA102701-08 ( U.S. NIH Grant/Contract )
CDR0000613100 ( Other Identifier: NCI )
First Posted: January 28, 2009    Key Record Dates
Last Update Posted: October 18, 2018
Last Verified: October 2018

Keywords provided by Gloria M. Petersen, Mayo Clinic:
recurrent pancreatic cancer
stage I pancreatic cancer
stage II pancreatic cancer
stage III pancreatic cancer
stage IV pancreatic cancer
recurrent islet cell carcinoma
pancreatic alpha cell carcinoma
pancreatic beta islet cell carcinoma
pancreatic delta cell carcinoma
pancreatic G-cell carcinoma

Additional relevant MeSH terms:
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Pancreatic Neoplasms
Pancreatic Diseases
Adenoma, Islet Cell
Digestive System Neoplasms
Neoplasms by Site
Endocrine Gland Neoplasms
Digestive System Diseases
Endocrine System Diseases
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type