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Intraoperative Blood Pressure and Cognitive Performance

This study has been completed.
Information provided by (Responsible Party):
Weill Medical College of Cornell University Identifier:
First received: January 21, 2009
Last updated: February 2, 2015
Last verified: February 2015
The purpose of this study is to prospectively determine the association between incidence of neurological morbidity and minimum fractional blood pressure reached during laminectomy procedures under general anesthesia in hypertensive and normotensive subjects 40 years old and older.

Cognitive Performance Hypertension

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Impact of Intraoperative Blood Pressure on Cognitive Performance in Patients With and Without Hypertension: a Prospective Observational Study

Further study details as provided by Weill Medical College of Cornell University:

Primary Outcome Measures:
  • post-operative cognitive performance [ Time Frame: 1 ]

Enrollment: 100
Study Start Date: January 2009
Study Completion Date: May 2014
Primary Completion Date: May 2014 (Final data collection date for primary outcome measure)


Ages Eligible for Study:   40 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
- individuals 40 years of age and older, undergoing laminectomy under general anesthesia.

Inclusion Criteria:

  • English as first language, or as a learned language as long as the patient is proficient
  • No history of any neurological disease with the exception of patients without functional impairment who suffered a single episode of transient ischemic attack
  • No history of axis I psychiatric diagnosis or drug abuse
  • 40 years old or older
  • Undergoing laminectomy under general anesthesia
  • Must not take antihypertensive medication for purposes other than treatment of hypertension

Exclusion Criteria:

  • Anyone who do not fit the inclusion criteria.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00827385

United States, New York
NewYork-Presbyterian Hospital-Weill Cornell Medical College
New York, New York, United States, 10065
Sponsors and Collaborators
Weill Medical College of Cornell University
  More Information

Responsible Party: Weill Medical College of Cornell University Identifier: NCT00827385     History of Changes
Other Study ID Numbers: 0809009986
Study First Received: January 21, 2009
Last Updated: February 2, 2015

Additional relevant MeSH terms:
Vascular Diseases
Cardiovascular Diseases processed this record on July 27, 2017