How Does 4 Weeks of Increased Fast Food Intake Affect Metabolism?
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|ClinicalTrials.gov Identifier: NCT00826631|
Recruitment Status : Completed
First Posted : January 22, 2009
Last Update Posted : January 22, 2009
Objective: To study the effect of fast food-based hyper-alimentation on liver enzymes and hepatic triglyceride content (HTGC)and metabolism.
Design: Prospective interventional study with parallel control group. Setting University Hospital of Linköping, Sweden. Participants: 12 healthy men and six healthy women with a mean (SD) age of 26 (6.6) years and a matched control group.
Intervention: Subjects in the intervention group aimed for a body weight increase of 5-15% by eating at least two fast food-based meals a day with the goal to double the regular caloric intake in combination with adoption of a sedentary lifestyle for four weeks.
Main outcome measures: Weekly changes of serum aminotransferases and HTGC measured by proton nuclear magnetic resonance-spectroscopy at baseline and after the intervention.
|Condition or disease||Intervention/treatment||Phase|
|Hyper-Alimentation Healthy||Procedure: Fast food arm||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||36 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||How Does 4 Weeks of Increased Fast Food Intake Affect Metabolism?|
|Study Start Date :||April 2006|
|Actual Primary Completion Date :||December 2007|
|Actual Study Completion Date :||January 2009|
Active Comparator: 1
Fast food intake, doubling of caloric intake, in combination with sedentary behavior (no exercise)
Procedure: Fast food arm
Doubling of regular caloric intake based on fast food, no exercise allowed
No Intervention: 2
Control group, parallel
- weight gain [ Time Frame: 1 month ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00826631
|University Hospital of Linkoping|
|Linkoping, Sweden, 58185|