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Fluorine-18-α-Methyltyrosine Positron Emission Tomography (18F-FMT PET) for Therapy Response in Lung Cancer
This study has been completed.
Sponsor:
Gunma University
Collaborator:
J~pharma
Information provided by:
Gunma University
ClinicalTrials.gov Identifier:
NCT00826033
First received: January 20, 2009
Last updated: NA
Last verified: January 2009
History: No changes posted
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Purpose
L-[3-18F]-α-methyltyrosine (18F-FMT) is an amino-acid tracer for positron emission tomography (PET). The investigators evaluated the value of 18F-FMT PET for the assessment of therapy response in patients with lung cancer as compared with that of 2-[18F]-fluoro-2-deoxy-D-glucose (18F-FDG) PET.
The patients with lung cancer underwent PET studies with 18F-FDG and 18F-FMT before and after radio-/chemotherapy. The investigators used the ratio of the SUVmax of the mediastinal (N2) lymph node to the SUVmax of the primary tumor (N/P ratio ). All patients were divided into two groups of N/P ratio<1 and N/P ratio≥1, and the survival time was estimated by Kaplan-Meier method.
| Condition |
|---|
| Non-Small Cell Lung Cancer |
| Study Type: | Observational |
| Study Design: | Time Perspective: Prospective |
| Official Title: | Fluorine-18-α-Methyltyrosine Positron Emission Tomography to Measure Therapy |
Resource links provided by NLM:
Genetics Home Reference related topics:
lung cancer
MedlinePlus related topics:
Lung Cancer
U.S. FDA Resources
Further study details as provided by Gunma University:
Eligibility| Ages Eligible for Study: | 20 Years and older (Adult, Senior) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
This study was conducted at the Gunma University Hospital.
Criteria
Inclusion Criteria:
- primary lung cancer All patients received first-line chemotherapy
Exclusion Criteria:
- Patients with diabetus mellitus
Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00826033
Please refer to this study by its ClinicalTrials.gov identifier: NCT00826033
Locations
| Japan | |
| Gunma University Graduate School of Medicine | |
| Gunma, Japan, 371-8511 | |
Sponsors and Collaborators
Gunma University
J~pharma
More Information
| ClinicalTrials.gov Identifier: | NCT00826033 History of Changes |
| Other Study ID Numbers: |
Mol Imaing 1 |
| Study First Received: | January 20, 2009 |
| Last Updated: | January 20, 2009 |
Keywords provided by Gunma University:
|
Fluorine-18-α-methyltyrosine Positron emission tomography Lung cancer chemotherapy monitoring |
Additional relevant MeSH terms:
|
Lung Neoplasms Carcinoma, Non-Small-Cell Lung Respiratory Tract Neoplasms Thoracic Neoplasms Neoplasms by Site Neoplasms Lung Diseases |
Respiratory Tract Diseases Carcinoma, Bronchogenic Bronchial Neoplasms Fluorides Cariostatic Agents Protective Agents Physiological Effects of Drugs |
ClinicalTrials.gov processed this record on June 23, 2017