Evaluation of Zapperclick Device for Relief From Mosquito Bites

This study is ongoing, but not recruiting participants.
Information provided by:
London School of Hygiene and Tropical Medicine
ClinicalTrials.gov Identifier:
First received: January 16, 2009
Last updated: NA
Last verified: January 2009
History: No changes posted
Mosquito bites commonly result in redness, swelling and itching. This study will determine if a device that emits a small piezo-electrical impulse can provide relief from these symptoms. Volunteers entering the study will have a mosquito bite on one forearm. Redness and irritation will be recorded periodically for 24 hours. Comparing data from subjects randomised to the treatment or a placebo device will be analysed to determine effectiveness of the product. We will also ask the subjects their view on how easy the product is to use and clarity of instructions provided.

Condition Intervention Phase
Insect Bites
Device: Zapperclick
Device: Inactivated zapperclick device
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Evaluation of a Piezoelectric Device (Zapperclick) for Relief From Mosquito Bites

Further study details as provided by London School of Hygiene and Tropical Medicine:

Primary Outcome Measures:
  • reduction in itching [ Time Frame: 24 hours ]

Secondary Outcome Measures:
  • reduction in erythema / oedema [ Time Frame: 24 hours ]

Estimated Enrollment: 120
Study Start Date: March 2008
Estimated Study Completion Date: February 2009
Primary Completion Date: November 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: 1
Use of zapperclick on mosquito bite
Device: Zapperclick
Device deliveres small piezoelectrical discharge to bite site (forearm)
Placebo Comparator: 2
use of inactivated zapperclick on mosquito bite
Device: Inactivated zapperclick device


Ages Eligible for Study:   16 Years to 60 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • known rection to mosquito bites
  • willing to attend clinic for 2 hours during measurements
  • informed written consent

Exclusion Criteria:

  • hypersensitivity to bites or stings
  • atopic allergy
  • pacemaker
  • pregnant / breast feeding
  • use of other medication including pain killers
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00825214

United Kingdom
London School of Hygiene & Tropical Medicine
London, United Kingdom, WC1E 7HT
Sponsors and Collaborators
London School of Hygiene and Tropical Medicine
  More Information

Responsible Party: Dr. Nigel Hill, Head of Unit, DCVBU. Principle Investigator, LSHTM
ClinicalTrials.gov Identifier: NCT00825214     History of Changes
Other Study ID Numbers: LSHTM/HILL/08/01 
Study First Received: January 16, 2009
Last Updated: January 16, 2009

Additional relevant MeSH terms:
Insect Bites and Stings
Bites and Stings
Chemically-Induced Disorders
Wounds and Injuries

ClinicalTrials.gov processed this record on January 19, 2017