Developing A Validated Measure of the Impact of Psoriasis on Chronic Quality of Life
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|ClinicalTrials.gov Identifier: NCT00823914|
Recruitment Status : Completed
First Posted : January 16, 2009
Last Update Posted : March 24, 2017
Objective of the study is to create and validate Chronic Quality of Life (CQOL) index that explores habits, career paths and other life choices psoriasis patients make as a result of coping with their disease that may not be impacted by therapy implemented at a given point in time.
- The investigators think this data will show that patients who were diagnosed at a young age will have worse chronic quality of life.
|Condition or disease|
As a visible disease, psoriasis can be embarrassing and psychosocially stressful in addition to physically uncomfortable. Patients' lives are affected in physical, psychological, social, sexual and occupational aspects. These burdens may cause patients to assume maladaptive habits and coping mechanisms, leading to a downward spiral in functioning within society, prohibiting patients from achieving their highest potential quality of life.
The investigators' study goal is to create and validate Chronic Quality of Life (CQOL) index that explores habits, career paths and other life choices psoriasis patients make as a result of coping with their disease that may not be impacted by therapy implemented at a given point in time. In creating this questionnaire and validating it the investigators will collect preliminary data. The investigators think this data will show that patients who were diagnosed at a young age will have worse chronic quality of life. In the long run, the investigators will use the CQOL index in studies in which patients are treated for psoriasis to determine which treatments can change a psoriasis patient's chronic quality of life. This information will be used to create guidelines for treatment focused on achieving a patient's optimal quality of life.
Another aspect that the investigators would like to look at is the skin carotenoid levels in the psoriasis population. Previous studies showed that psoriasis patients had lower levels of skin carotenoids when compared to healthy volunteers. This observation was not statistically significant perhaps due to a small sample size (21 subjects in the psoriasis group and 35 subjects in the control group). Skin carotenoid levels measurement is optional for study subjects.
|Study Type :||Observational|
|Actual Enrollment :||116 participants|
|Official Title:||Developing A Validated Measure of the Impact of Psoriasis on Chronic Quality of Life|
|Study Start Date :||December 2008|
|Actual Primary Completion Date :||December 2013|
|Actual Study Completion Date :||December 2013|
- Chronic Quality of Life (CQOL) survey validation. [ Time Frame: 1 year ]
- Skin carotenoid levels [ Time Frame: 1 year ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00823914
|United States, Massachusetts|
|Massachusetts General Hospital CURTIS|
|Boston, Massachusetts, United States, 02114|
|Principal Investigator:||Alexa Kimball, MD, MPH||Massachusetts General Hospital|