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Effects of Ritalin on Postural Stability of Old Adults

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ClinicalTrials.gov Identifier: NCT00817960
Recruitment Status : Completed
First Posted : January 7, 2009
Last Update Posted : June 20, 2012
Information provided by (Responsible Party):
Soroka University Medical Center

Brief Summary:
Experimental design overview The proposed project is a prospective experimental study design. independent old adults(age 65 years old and older) who do not suffer from balance problems willing to participate in the study will be tested with well-established measuring techniques of Balance control before and 2 hours after taking of Methylphenidate (Ritalin) in the movement and Rehabilitation Laboratory at BGU. An automated algorithm will be used to extract standardized stabilogram-diffusion parameters from each of the COP data sets collected during quiet standing. These parameters include diffusion coefficients, critical displacement, critical time and scaling exponents for both lateral and anterior-posterior sway directions (Collins & De Luca, 1993). For each of the conditions (before and 1 hour after the use of Ritalin) in three task conditions single task; dual task (concentrating and identifying specific music); and just Listening to a relaxing music. Participants will be required to stand on the platform 10 times for 30 s. For each trial, they will be instructed to sway as little as possible.

Condition or disease Intervention/treatment
Postural Imbalance Drug: Methylphenidate

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 30 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Effects of Methylphenidate on Postural Stability of Old Adults Under Single and Dual Task Conditions.
Study Start Date : July 2011
Primary Completion Date : January 2012
Study Completion Date : June 2012

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: Methylphenidate Drug: Methylphenidate
The effect of ritalin on postural stability of old adults (65 years old and over) will be measured using RCT study design

Primary Outcome Measures :
  1. Postural sway measures [ Time Frame: Time 1: pre test` and hour later time 2: post testinng proceedure ]

Information from the National Library of Medicine

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Ages Eligible for Study:   65 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Age 65 years old and older
  • independent elderly adults
  • do not suffer from balance prblems
  • minimental score 24 and above

Exclusion Criteria:

  • old adults who suffer from neurological disease or stroke
  • old adults who suffer from psychiatric state
  • old adults who suffer from orthopedic condition (1/2 a year after a fracture in the lower limb)
  • old adults who suffer from heart conditions
  • old adults who suffer from blindness

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00817960

Beer-Sheva, Israel, 84105
Sponsors and Collaborators
Soroka University Medical Center
Principal Investigator: Itshak Melzer, PhD Ben-gurion University of the Negev, Beer-Sheva, Israel
Study Chair: Zmir Shorer, m Soroka University Medical Centar
Study Director: Yan Press, MD Soroka University Medical Center

Responsible Party: Soroka University Medical Center
ClinicalTrials.gov Identifier: NCT00817960     History of Changes
Other Study ID Numbers: SOR476508CTIL
First Posted: January 7, 2009    Key Record Dates
Last Update Posted: June 20, 2012
Last Verified: December 2008

Keywords provided by Soroka University Medical Center:
Dual tasking
Postural Control
Methylphenidate (Ritalin)
old adults

Additional relevant MeSH terms:
Central Nervous System Stimulants
Physiological Effects of Drugs
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents