Sleep Disturbances as a Non-traditional Risk Factor in CKD-Actigraphy (CRIC)
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To test if usual at home night time sleep duration as measured with activity monitors and questionnaires will predict changes in kidney function as measured by kidney filtration rate and of cardiovascular function as measured by C-reactive protein in the blood. The study will explore the role of decreased sleep time or decreased sleep quality as a non-traditional risk factor for the progression of CKD and for the development of cardiovascular disease in CKD.
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Ages Eligible for Study:
21 Years to 74 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
CKD subjects; healthy volunteers
Mild to Moderate CKD
Healthy controls age and gender matched to CKD subjects
Regular bedtimes of at least 6h/night, sedentary lifestyle
Current or previous dialysis for more than 1 month
Hemoglobin < 10.5 g/dl
Treatment with EProcrit, Epogen, or Aranesp
Bone or organ transplant,
Use of immunosuppressive drugs within past 6 months