Trial record 3 of 61 for:    Open Studies | "Colonic Neoplasms"

The Effects of Exercise Training on the Health-related Fitness of Colon Cancer Survivors

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2012 by AHS Cancer Control Alberta.
Recruitment status was  Recruiting
Information provided by (Responsible Party):
AHS Cancer Control Alberta ( Alberta Health Services ) Identifier:
First received: December 19, 2008
Last updated: April 4, 2012
Last verified: April 2012
Recent studies have suggested that individuals diagnosed with colon cancer who are inactive and/or overweight, may have poorer survival outcomes. Exercise training has been shown to improve fitness and body composition in other cancer survivor groups. The investigators hypothesize that an exercise training program will be a safe, feasible, and effective intervention to improve the fitness and body composition of a group of colon cancer survivors.

Condition Intervention Phase
Colonic Neoplasms
Behavioral: Exercise Training
Other: Usual Care
Phase 2
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Supportive Care
Official Title: The Effects of Exercise Training on the Health-related Fitness of Colon Cancer Survivors: a Randomized Controlled Trial

Resource links provided by NLM:

Further study details as provided by AHS Cancer Control Alberta:

Primary Outcome Measures:
  • Safety (Monitoring for Adverse Events) [ Time Frame: 12 Weeks ] [ Designated as safety issue: Yes ]

Secondary Outcome Measures:
  • Change in Aerobic Capacity [ Time Frame: Baseline and 12 Weeks ] [ Designated as safety issue: No ]
  • Change in body composition [ Time Frame: Baseline and 12 Weeks ] [ Designated as safety issue: No ]
  • Feasibility (Adherence to the exercise training program) [ Time Frame: 12 weeks ] [ Designated as safety issue: Yes ]

Estimated Enrollment: 52
Study Start Date: March 2009
Estimated Study Completion Date: May 2012
Estimated Primary Completion Date: May 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Behavioral: Exercise Training
The exercise group will perform supervised stationary cycle ergometer exercise 3 times per week for 12 weeks and be progressed from 15 to 45 minutes and 60% to 110% of the power output obtained at V02peak. Resistance training will be completed twice per week and will include exercises for all major muscle groups. The training will progress from 60% to 80% of 1RM over the course of the intervention.
Usual Care, no intervention
Other: Usual Care
Usual Care


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Histologically confirmed Stage II or III colon cancer diagnosis
  • Less than or equal to 1 year since the completion of all adjuvant treatment
  • Negative Physical Activity Readiness Questionnaire (PAR-Q) or completed Physical Activity Readiness Medical Examination (PARmed-X) form
  • 18 years of age or older
  • Ability to understand and provide written informed consent in English
  • Willingness to be randomized
  • Willingness to complete outcome measures at each assessment time point
  • Available for the duration of study intervention period
  • Able to travel to our fitness centre 3/week for the study period

Exclusion Criteria:

  • Any absolute contraindication to to exercise testing or training
  • Evidence of active disease (metastatic, recurrent, or unresectable colon cancer)
  • Any uncontrolled medical condition or psychiatric illness that would prevent completion of the exercise program or interfere with the study assessments
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00813540

Contact: Christopher Sellar, M.Sc. (780) 492-2829

Canada, Alberta
Cross Cancer Institue Recruiting
Edmonton, Alberta, Canada, T6G 1Z2
Contact: Christopher Sellar, M.Sc.    (780) 492-2829   
Sub-Investigator: Heather J Au, M.D         
Sub-Investigator: Gordon Bell, Ph.D         
Sponsors and Collaborators
Alberta Health Services
Principal Investigator: Kerry Courneya, Ph.D. AHS Cancer Control Alberta
  More Information

No publications provided

Responsible Party: AHS Cancer Control Alberta ( Alberta Health Services ) Identifier: NCT00813540     History of Changes
Other Study ID Numbers: G1-23950 
Study First Received: December 19, 2008
Last Updated: April 4, 2012
Health Authority: Canada: Health Canada

Keywords provided by AHS Cancer Control Alberta:
Colonic Neoplasms
Aerobic Exercise
Weight Lifting
Body Composition

Additional relevant MeSH terms:
Colonic Neoplasms
Colonic Diseases
Colorectal Neoplasms
Digestive System Diseases
Digestive System Neoplasms
Gastrointestinal Diseases
Gastrointestinal Neoplasms
Intestinal Diseases
Intestinal Neoplasms
Neoplasms by Site processed this record on February 04, 2016