Analgesic Ointment on Temporomandibular Joint and Masticatory Muscle Pain
The purpose of this study is to compare the effectiveness of using topical cream of Ping On Ointment and using Vaseline cream in the treatment of temporomandibular joint (TMJ) and masticatory muscle pain, in order to establish the true efficacy of Ping On Ointment. Both Ping On Ointment and Vaseline are considered intervention.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Effect of an Analgesic Ointment on the Relief of Temporomandibular Joint and Masticatory Muscle Pain: a Randomized, Double Blinded, Placebo-controlled Study.|
- The Efficacy in the Treatment of TMJ and Muscle Pain [ Time Frame: 4 weeks ] [ Designated as safety issue: No ]
The efficacy in the treatment of TMJ and muscle pain is measured by a visual analogue scale (VAS).
The VAS consists of a 100 mm line, anchored with the extremes of pain intensity represented as "no pain" ( 0 mm) and " worst pain possible" ( 100 mm).
- The Mandibular Function. [ Time Frame: 4 weeks ] [ Designated as safety issue: No ]The mandibular function, the maximal comfortable mandibular opening measured in millimeters at the subjects's maximum incisor to incisor mouth opening using a ruler.
|Study Start Date:||April 2007|
|Study Completion Date:||September 2008|
|Primary Completion Date:||June 2008 (Final data collection date for primary outcome measure)|
Experimental: Ping On Ointment
Ping On Ointment
Drug: Ping On Ointment
Ping On Ointment
Placebo Comparator: Vaseline
Vaseline with minor trace of Ping On ointment to give medicinal smell
Other Name: Vaseline
Aims: To compare the effectiveness of using topical cream of Ping On Ointment and using Vaseline cream in the treatment of temporomandibular joint (TMJ) and masticatory muscle pain, in order to establish the true efficacy of Ping On Ointment. Methods: In this randomized, double-blinded, placebo-controlled trial, 55 subjects with TMJ and/or masticatory pain (Group 1 patients according to the Research Diagnostic Criteria for Temporomandibular Disorder (RDC/TMD) received Ping On Ointment for 4 weeks; or placebo for 4 weeks. Subjects were evaluated with standard measures of efficacy: pain intensity measured by visual analogue scale and maximal comfortable mandibular opening, at baseline and again after 4 weeks of treatment.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00812604
|China, Hong Kong|
|Faculty of Dentistry, The University of Hong Kong|
|Hong Kong, Hong Kong, China|
|Principal Investigator:||Ricky W. K. Wong, PhD||Orthodontics, Faculty of Dentistry, University of Hong Kong|