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Cognitive Behavioral Therapy for Depression in Parkinson's Disease

This study has been terminated.
National Parkinson Foundation
Information provided by:
Oregon Health and Science University Identifier:
First received: December 17, 2008
Last updated: October 23, 2014
Last verified: December 2008

The purpose of this pilot program is to develop and evaluate a new treatment program for depression in Parkinson's disease (PD). The treatment uses Cognitive Behavior Therapy(CBT)to teach patients how to become more aware of their thoughts and feelings and to change thinking patterns and behaviors that may be related to depressive symptoms. This is the first time that this treatment has been used in a group setting for depression in PD.

Target population is patients in the Movement Disorders Clinic at Oregon Health & Science University who have Parkinson's disease and mild to moderate depression.

Condition Intervention
Parkinson's Disease Depression Behavioral: Cognitive Behavioral Therapy

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care
Official Title: Depression in Parkinson's Disease: A Pilot Project Using Cognitive Behavioral Therapy (CBT) to Improve Depression and Coping

Resource links provided by NLM:

Further study details as provided by Oregon Health and Science University:

Primary Outcome Measures:
  • The change in CESD score [ Time Frame: Baseline and 10 weeks ]

Enrollment: 12
Study Start Date: January 2009
Study Completion Date: December 2009
Primary Completion Date: September 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
All subjects in same investigative group with same CBT intervention.
Behavioral: Cognitive Behavioral Therapy
Individual interviews and group discussion/training.


Ages Eligible for Study:   35 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Parkinson's disease, mild to moderate depression, seen at Oregon Health & Science University

Exclusion Criteria:

  • Suicidal
  • Cognitive impairment with MOCA <26
  Contacts and Locations
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Please refer to this study by its identifier: NCT00810628

United States, Oregon
Oregon Health & Science University
Portland, Oregon, United States, 97239
Sponsors and Collaborators
Oregon Health and Science University
National Parkinson Foundation
Principal Investigator: Julie H. Carter, MS Oregon Health and Science University
Principal Investigator: Kristine Hanna, PhD Oregon Health and Science University
  More Information

Responsible Party: Julie Carter, MS, ANP, Oregon Health & Science University Identifier: NCT00810628     History of Changes
Other Study ID Numbers: OHSUIRB4613
Study First Received: December 17, 2008
Last Updated: October 23, 2014

Keywords provided by Oregon Health and Science University:
Parkinson's disease
Parkinson's disease with mild to moderate depression.

Additional relevant MeSH terms:
Depressive Disorder
Parkinson Disease
Behavioral Symptoms
Mood Disorders
Mental Disorders
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases processed this record on September 21, 2017