Cognitive Behavioral Therapy for Depression in Parkinson's Disease

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00810628
Recruitment Status : Terminated
First Posted : December 18, 2008
Last Update Posted : October 24, 2014
National Parkinson Foundation
Information provided by:
Oregon Health and Science University

Brief Summary:

The purpose of this pilot program is to develop and evaluate a new treatment program for depression in Parkinson's disease (PD). The treatment uses Cognitive Behavior Therapy(CBT)to teach patients how to become more aware of their thoughts and feelings and to change thinking patterns and behaviors that may be related to depressive symptoms. This is the first time that this treatment has been used in a group setting for depression in PD.

Target population is patients in the Movement Disorders Clinic at Oregon Health & Science University who have Parkinson's disease and mild to moderate depression.

Condition or disease Intervention/treatment Phase
Parkinson's Disease Depression Behavioral: Cognitive Behavioral Therapy Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 12 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care
Official Title: Depression in Parkinson's Disease: A Pilot Project Using Cognitive Behavioral Therapy (CBT) to Improve Depression and Coping
Study Start Date : January 2009
Actual Primary Completion Date : September 2009
Actual Study Completion Date : December 2009

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: 1
All subjects in same investigative group with same CBT intervention.
Behavioral: Cognitive Behavioral Therapy
Individual interviews and group discussion/training.

Primary Outcome Measures :
  1. The change in CESD score [ Time Frame: Baseline and 10 weeks ]

Information from the National Library of Medicine

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Ages Eligible for Study:   35 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Parkinson's disease, mild to moderate depression, seen at Oregon Health & Science University

Exclusion Criteria:

  • Suicidal
  • Cognitive impairment with MOCA <26

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00810628

United States, Oregon
Oregon Health & Science University
Portland, Oregon, United States, 97239
Sponsors and Collaborators
Oregon Health and Science University
National Parkinson Foundation
Principal Investigator: Julie H. Carter, MS Oregon Health and Science University
Principal Investigator: Kristine Hanna, PhD Oregon Health and Science University

Responsible Party: Julie Carter, MS, ANP, Oregon Health & Science University Identifier: NCT00810628     History of Changes
Other Study ID Numbers: OHSUIRB4613
First Posted: December 18, 2008    Key Record Dates
Last Update Posted: October 24, 2014
Last Verified: December 2008

Keywords provided by Oregon Health and Science University:
Parkinson's disease
Parkinson's disease with mild to moderate depression.

Additional relevant MeSH terms:
Depressive Disorder
Parkinson Disease
Behavioral Symptoms
Mood Disorders
Mental Disorders
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases