Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
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ClinicalTrials.gov Identifier: NCT00810225 |
Recruitment Status :
Completed
First Posted : December 18, 2008
Last Update Posted : June 18, 2018
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Determine if:
- genetic differences of CNDP1 gene
- the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents
- psychometric
- other variables can differentiate between veterans of the 1990-1991 Persian Gulf War who have autonomic, neurological and other symptoms and those without these complaints.
Condition or disease |
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Gulf War Illness Persian Gulf War Syndrome |
Study Type : | Observational |
Actual Enrollment : | 516 participants |
Observational Model: | Case-Control |
Time Perspective: | Cross-Sectional |
Official Title: | CNDP1 Polymorphisms in Gulf War Illness (GWI) |
Study Start Date : | August 2008 |
Actual Primary Completion Date : | July 2011 |
Actual Study Completion Date : | July 2011 |
Group/Cohort |
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1
GWI: veterans of the 1990-1991 Persian Gulf War who have autonomic, neurological and other symptoms
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2
HC: healthy veterans of the 1990-1991 Persian Gulf War
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Ages Eligible for Study: | Child, Adult, Older Adult |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
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Evidence of military enlistment between August 1, 1990 and July 31, 1991, and deployment for 30 consecutive days to:
- Persian Gulf waters and adjacent land areas
- Other global locations
- U.S. only
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Status prior to 1990 and 1991:
- Active duty
- National Guard
- Reserves
Exclusion Criteria:
- Current active duty military personnel
- Any one who was not active duty military personnel between August 1, 1990 and July 31, 1991
- HIV/AIDS; pregnancy or lactation; potential hepatitis; drug addiction; chronic inflammatory, infectious, or autoimmune medical illnesses not associated with GWI; incarceration; dementia, other cognitive limitation; or reliance on a care-giver in order to respond to the questionnaires and other study tests.
Amputations of one or both hands and forearms will be permitted but hand grip tests will not be tested

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00810225
United States, District of Columbia | |
Georgetown University | |
Washington, District of Columbia, United States, 20007 |
Principal Investigator: | James N Baraniuk, MD | Georgetown University |
Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | James Baraniuk, MD, Professor of Medicine, Georgetown University |
ClinicalTrials.gov Identifier: | NCT00810225 |
Other Study ID Numbers: |
2008-012 USAMRMC PR# W81XWH-07-1-0618 HRPO Log No. A-14542.1 |
First Posted: | December 18, 2008 Key Record Dates |
Last Update Posted: | June 18, 2018 |
Last Verified: | June 2018 |
CNDP1 carnosine dipeptidase 1 Persian Gulf War Gulf War Syndrome GWI Gulf War Illness Exercise |
Chronic Fatigue Fibromyalgia Veterans Irritable Bowel Syndrome Migraine headaches Neuropathy Multiple Chemical Sensitivity |
Syndrome Persian Gulf Syndrome Disease Pathologic Processes Occupational Diseases |