Role of Chest Ultrasound in Diagnosing and Follow-up of Pneumonia
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|ClinicalTrials.gov Identifier: NCT00808457|
Recruitment Status : Completed
First Posted : December 15, 2008
Last Update Posted : August 15, 2011
The study of a large number of patients (at least 200 patients) from several European centres aims to investigate the value of chest ultrasound in diagnosing and checking the course of pneumonia as compared to a chest X-ray film in two planes and - in case of a controversial X-ray finding- as compared to low-dose CT.
An X-ray finding is regarded controversial, if infiltrates cannot be reliably excluded or not reliably represented and if a definite diagnosis is, thus, not possible. A low-dose CT is indicated even in case of a positive chest ultrasound and negative X-ray finding. Sonographic recording and characterization of pneumonic infiltrates is performed both at the time of diagnosing and in the further course under therapy.
|Condition or disease|
The primary target criterion is
• Assessing the sensitivity of chest ultrasound in diagnosing pneumonia.
Secondary target criteria comprise
- Assessing specificity, negative and positive predictive value of chest ultrasound at the time of diagnosing,
- Characterizing pneumonic infiltrates at the time of diagnosing and further course,
- Describing the association between clinical, X-ray and sonographic findings in the course of pneumonia.
The tertiary target criterion includes
• Characterizing the range of pathogens detected by microbiological examination.
|Study Type :||Observational|
|Actual Enrollment :||397 participants|
|Official Title:||Role of Chest Ultrasound in Diagnosing and Follow-up of Pneumonia. Prospective Comparison Between X-ray Chest Film in Two Planes and "Low-dose" Spiral Computed Tomography|
|Study Start Date :||September 2007|
|Actual Primary Completion Date :||February 2011|
|Actual Study Completion Date :||February 2011|
|patients with suspected pneumonia|
- sensitivity of chest ultrasound in diagnosing pneumonia [ Time Frame: baseline diagnostic ]
- Specificity [ Time Frame: baseline diagnostic ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00808457
|Pneumology, Friedrich-Schiller University Jena|
|Jena, Thüringen, Germany, 07740|