Early Detection and Prediction of Chemotherapy Induced Cardiac Toxicity in Breast Cancer Patients
The goal of this clinical research study is to learn whether different ways of viewing echocardiogram pictures along with blood tests can help to see heart-related side effects of chemotherapy and trastuzumab earlier than the usual tests.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Early Detection and Prediction of Chemotherapy Induced Cardiac Toxicity in Breast Cancer Patients|
- Predictors of cardio-toxicity in female patients with breast cancer exposed to trastuzumab +/- previous anthracycline agents [ Time Frame: Baseline to 12 months ] [ Designated as safety issue: No ]Identification of heart-related side effects of chemotherapy and trastuzumab using echocardiogram pictures plus blood tests.
|Study Start Date:||November 2008|
|Study Completion Date:||August 2011|
|Primary Completion Date:||August 2011 (Final data collection date for primary outcome measure)|
Echocardiogram + Blood Test
Additional Echocardiogram views performed in 5-10 minutes of regularly scheduled echocardiograms plus blood tests measuring of hormones and metabolic proteins (such as sugars and acids).
Additional views performed in 5-10 minutes of regularly scheduled echocardiograms.Procedure: Blood Test
Measuring of hormones and metabolic proteins (such as sugars and acids).
Show Detailed Description
Please refer to this study by its ClinicalTrials.gov identifier: NCT00806507
|United States, Massachusetts|
|Partners Healthcare Systems|
|Boston, Massachusetts, United States, 02199|
|United States, Texas|
|UT MD Anderson Cancer Center|
|Houston, Texas, United States, 77030|
|Principal Investigator:||Jose Banchs, MD||M.D. Anderson Cancer Center|