Ultrasound and X-ray in Detecting Articular Cartilage Calcification (chondro)

This study has been completed.
Information provided by:
University Hospital, Limoges
ClinicalTrials.gov Identifier:
First received: November 20, 2008
Last updated: September 3, 2010
Last verified: September 2010
Prospective study with an echography of the 2 knees and radiography of the 2 knees (front and profile) for each patient. If found calcification on ultrasound further examination with ultrasound wrists, hips and shoulders.

Condition Intervention
Articular Cartilage Calcification
Procedure: Echography

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Concordance Entre l'échographie du Genou et la Radiographie Standard Dans la détection Des Calcifications Dans le Cadre de la Chondrocalcinose Articulaire

Resource links provided by NLM:

Further study details as provided by University Hospital, Limoges:

Primary Outcome Measures:
  • Knee calcification detected by echography and radiography [ Time Frame: Day 1 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Calcification description and other localisations finding [ Time Frame: Day 1 ] [ Designated as safety issue: No ]

Estimated Enrollment: 166
Study Start Date: May 2008
Study Completion Date: September 2010
Primary Completion Date: September 2010 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: Echography
Detailed Description:

Osteo-articular echography is currently recognized as an important development among rheumatologists.

Chondrocalcinosis, which can promote joint inflammation and cartilage degeneration, is highly prevalent in elderly subjects.

Osteo-articular echography is currently reconized as an important development among rheumatologists and can efficiently use to detect Chondrocalcinosis.

The aim of this study is to find a correlation between radiography and echography in detecting CPPD crystal deposition, on a sample of patients and more important with a new generation of ultrasound with a probe superficial performance.

166 patients will be enrolled in this trial and an echography and a radiography of the 2 knees (front and profile) will be done for each patient.

Ih the echography show a calcification, further exams with wrists, hips shoulders echographies will be conducted.

In case of liquid epanchement, analysis of the liquid will be carried in order to eliminate the differential diagnostic including septic arthritis


Ages Eligible for Study:   70 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • patient> 70 years
  • articular pathology of the knee
  • consent signed

Exclusion Criteria:

  • Not covered by social security
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00797537

Service de Rhumatologie
Limoges, France, 87000
Sponsors and Collaborators
University Hospital, Limoges
  More Information

Responsible Party: CHU de Limoges
ClinicalTrials.gov Identifier: NCT00797537     History of Changes
Other Study ID Numbers: I07027/chondrocalcinose 
Study First Received: November 20, 2008
Last Updated: September 3, 2010
Health Authority: France: Direction Générale de la Santé

Keywords provided by University Hospital, Limoges:
Inflammation of bone and cartilage

Additional relevant MeSH terms:
Calcium Metabolism Disorders
Joint Diseases
Metabolic Diseases
Musculoskeletal Diseases

ClinicalTrials.gov processed this record on May 25, 2016