Outcomes of Mechanically Ventilated Patients With Low Serum Testosterone
|ClinicalTrials.gov Identifier: NCT00797433|
Recruitment Status : Completed
First Posted : November 25, 2008
Last Update Posted : September 21, 2010
This is a study to determine the testosterone serum levels in male patient with acute respiratory failure requiring mechanical ventilation. The objective is to determine if low levels exist in this population and if it correlates with length of mechanical ventilation.
Hypothesis: Serum testosterone levels in mechanically ventilated male patients are significantly decreased from normal levels and correlate with disease severity and outcomes.
|Condition or disease|
|Acute Respiratory Failure|
- To confirm and quantify the presence of hypotestosteronemia in critically ill male patients with acute respiratory failure requiring mechanical ventilation via endotracheal intubation.
- To correlate serum testosterone levels with disease severity, short-term outcomes, and survival in mechanically ventilated male patients.
- To determine if demographic patient characteristics, such as age, admitting diagnosis, or the presence of co-morbidities, affect serum testosterone levels during mechanical ventilation.
|Study Type :||Observational|
|Estimated Enrollment :||28 participants|
|Official Title:||Outcomes of Mechanically Ventilated Patients With Low Serum Testosterone|
|Study Start Date :||December 2008|
|Actual Primary Completion Date :||August 2010|
|Actual Study Completion Date :||August 2010|
All male patients with acute respiratory failure requiring mechanical ventilation
- Serum testosterone level [ Time Frame: Day 1, 3 and 7 ]
- Length of mechanical ventilation [ Time Frame: Days ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00797433
|United States, Texas|
|University of Texas Health Science Center at Houston|
|Houston, Texas, United States, 77030|
|Principal Investigator:||Khalid F Almoosa, MD||University of Texas|