Propofol-butorphanol Anesthesia During Uterine Curettage (PABADUC)
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00795314 |
Recruitment Status :
Completed
First Posted : November 21, 2008
Last Update Posted : July 15, 2009
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Abortion Curettage | Drug: Fentanyl Citrate Drug: Butorphanol Tartrate | Phase 4 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 150 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) |
Primary Purpose: | Treatment |
Official Title: | Propofol-butorphanol Combined Anesthesia During Uterine Curettage on Abortion |
Study Start Date : | November 2008 |
Actual Primary Completion Date : | July 2009 |
Actual Study Completion Date : | July 2009 |

Arm | Intervention/treatment |
---|---|
Active Comparator: 1
Propofol-fentanyl combined anesthesia
|
Drug: Fentanyl Citrate
Combined anesthesia with propofol (2-2.5mg/kg) and fentanyl (5 μg)
Other Names:
|
Experimental: 2
Propofol-butorphanol combined anesthesia
|
Drug: Butorphanol Tartrate
Combined anesthesia with propofol (2-2.5 mg/kg) and butorphanol (1mg)
Other Names:
|
- Intraoperative awareness [ Time Frame: During the whole process of anesthesia ]
- Bispectral Index (BIS) value [ Time Frame: During the whole process of anesthesia ]
- Anesthetic consumptions [ Time Frame: From the start of operation to the end of surgical procedures ]
- Postoperative pain [ Time Frame: Since the end of the operation to 48 h follow-up. ]
- Postoperative bleeding [ Time Frame: Since the end of operation to 48 h follow-up ]

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 19 Years to 45 Years (Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- ASA status I-II;
- Performing abortion operation (medical- or drug-induced);
- Requiring painless abortion;
Exclusion Criteria:
- < 19yrs, and >= 45yrs;
- History of central active drugs administration;
- Drug abuse;
- Hypertension;
- Diabetes;
- Any other chronic diseases;
- Allergy to the study drugs;
- Habit of over-volume alcohol drinking;
- Records of history of centrally active drug use and psychiatry;
- Any organic disorders.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00795314
China, Jiangsu | |
Nanjing Maternal and Child Health Care Hospital | |
Nanjing, Jiangsu, China, 210004 |
Study Chair: | XiaoFeng Shen, MD | Nanjing Medical University |
Responsible Party: | XiaoFeng Shen, Nanjing Medical University |
ClinicalTrials.gov Identifier: | NCT00795314 |
Other Study ID Numbers: |
NMU-2008-FY10MZ31 NJFY0811-MZ02 |
First Posted: | November 21, 2008 Key Record Dates |
Last Update Posted: | July 15, 2009 |
Last Verified: | July 2009 |
Opioids General anesthesia |
Fentanyl Butorphanol Analgesics, Opioid Narcotics Central Nervous System Depressants Physiological Effects of Drugs Analgesics Sensory System Agents |
Peripheral Nervous System Agents Adjuvants, Anesthesia Anesthetics, Intravenous Anesthetics, General Anesthetics Antitussive Agents Respiratory System Agents Narcotic Antagonists |