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Reproducibility of Magnetic Resonance Myocardial Salvage Index

This study has been completed.
Information provided by:
University of Leipzig Identifier:
First received: November 19, 2008
Last updated: NA
Last verified: November 2008
History: No changes posted
The myocardial salvage assessed by using multimodal cardiac magnetic resonance imaging is a rather new technique which can be used as a surrogate endpoint to reduce the sample size in studies comparing different reperfusion strategies in myocardial infarction. As reproducibility of myocardial salvage has not been evaluated appropriately, we aim to scan 20 patients on 2 subsequent days to evaluate reproducibility of myocardial salvage index.

Condition Intervention
Myocardial Infarction
Device: second magnetic resonance imaging scan

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Reproducibility of Myocardial Salvage Index in Acute Myocardial Infarction by Cardiac Magnetic Resonance Imaging

Resource links provided by NLM:

Further study details as provided by University of Leipzig:

Primary Outcome Measures:
  • Myocardial salvage index reproducibility [ Time Frame: 2 days ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • infarct size reproducibility [ Time Frame: 2 days ] [ Designated as safety issue: No ]
  • area at risk reproducibility [ Time Frame: 2 days ] [ Designated as safety issue: No ]
  • microvascular obstruction reproducibility [ Time Frame: 2 days ] [ Designated as safety issue: No ]

Groups/Cohorts Assigned Interventions
Acute myocardial infarction patients Device: second magnetic resonance imaging scan


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
ST-elevation myocardial infarction

Inclusion Criteria:

  • ST-elevation myocardial infarction
  • Primary percutaneous coronary intervention

Exclusion Criteria:

  • Contraindications for magnetic resonance imaging
  Contacts and Locations
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Please refer to this study by its identifier: NCT00794300

University of Leipzig - Heart Center
Leipzig, Germany, 04289
Sponsors and Collaborators
University of Leipzig
Principal Investigator: Holger Thiele, MD Heartcenter Leipzig GmbH
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00794300     History of Changes
Other Study ID Numbers: Repro100 
Study First Received: November 19, 2008
Last Updated: November 19, 2008
Health Authority: Germany: Ethics Commission

Keywords provided by University of Leipzig:
contrast agent
magnetic resonance imaging
infarct size
myocardial salvage index
myocardial salvage assessment

Additional relevant MeSH terms:
Myocardial Infarction
Pathologic Processes
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases processed this record on December 07, 2016