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Reproducibility of Magnetic Resonance Myocardial Salvage Index

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ClinicalTrials.gov Identifier: NCT00794300
Recruitment Status : Completed
First Posted : November 20, 2008
Last Update Posted : November 20, 2008
Information provided by:

Study Description
Brief Summary:
The myocardial salvage assessed by using multimodal cardiac magnetic resonance imaging is a rather new technique which can be used as a surrogate endpoint to reduce the sample size in studies comparing different reperfusion strategies in myocardial infarction. As reproducibility of myocardial salvage has not been evaluated appropriately, we aim to scan 20 patients on 2 subsequent days to evaluate reproducibility of myocardial salvage index.

Condition or disease Intervention/treatment
Myocardial Infarction Device: second magnetic resonance imaging scan

Study Design

Study Type : Observational
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Reproducibility of Myocardial Salvage Index in Acute Myocardial Infarction by Cardiac Magnetic Resonance Imaging

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts

Group/Cohort Intervention/treatment
Acute myocardial infarction patients Device: second magnetic resonance imaging scan

Outcome Measures

Primary Outcome Measures :
  1. Myocardial salvage index reproducibility [ Time Frame: 2 days ]

Secondary Outcome Measures :
  1. infarct size reproducibility [ Time Frame: 2 days ]
  2. area at risk reproducibility [ Time Frame: 2 days ]
  3. microvascular obstruction reproducibility [ Time Frame: 2 days ]

Eligibility Criteria

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
ST-elevation myocardial infarction

Inclusion Criteria:

  • ST-elevation myocardial infarction
  • Primary percutaneous coronary intervention

Exclusion Criteria:

  • Contraindications for magnetic resonance imaging
Contacts and Locations

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00794300

University of Leipzig - Heart Center
Leipzig, Germany, 04289
Sponsors and Collaborators
University of Leipzig
Principal Investigator: Holger Thiele, MD Heartcenter Leipzig GmbH
More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00794300     History of Changes
Other Study ID Numbers: Repro100
First Posted: November 20, 2008    Key Record Dates
Last Update Posted: November 20, 2008
Last Verified: November 2008

Keywords provided by University of Leipzig:
contrast agent
magnetic resonance imaging
infarct size
myocardial salvage index
myocardial salvage assessment

Additional relevant MeSH terms:
Myocardial Infarction
Pathologic Processes
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases